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View Structure Prediction Details

Protein: Hey-PA
Organism: Drosophila melanogaster
Length: 425 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hey-PA.

Description E-value Query
Range
Subject
Range
gi|115646541 - gi|115646541|gb|ABJ17078.1| RT01017p [Drosophila melanogaster]
212.0 [0..1] [425..1]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDHNMHVNAP SLHHWGYAAG PGVVMPGATA TTPQSHWVPP PQSHHSAHSN HSHGHSQGHS  60
   61 HGIGSLKRTL SESDCDDLYS E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [82-163]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESSKEQISPS EPGSCQLMSR KKRRGVIEKK RRDRINSSLT ELKRLVPSAY EKQGSAKLEK  60
   61 AEILQLTVEH LKSLQSKTLD SL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.221849
Match: 1an4A
Description: Usf B/HLH domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.12507195426228 bayes_pls_golite062009
nucleic acid binding 0.43204604575196 bayes_pls_golite062009
DNA binding 0.40884226851256 bayes_pls_golite062009
transcription regulator activity 0.31759335140578 bayes_pls_golite062009
transcription factor activity 0.09721565916723 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [164-204]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYDPQRVAMD YHIIGFRECA AEVARYLVTI EGMDIQDPLR L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 2db7A
Description: No description for 2db7A was found.

Predicted functions:

Term Confidence Notes
binding 0.533405820900955 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [205-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLMSHLQYFV QQRELSAKSC ASPGGWSPAA PSSSGYQPNC AAAPYQSYAA PANPGAYVSS  60
   61 YPTLSASPSQ QAQQLGGRTS VSRTSGSAVT ESLPSHDLHS DSSSQQQQQQ QQQQQQQQQH 120
  121 QQQQHQQQQQ RTQTTPQPTQ QQHYTHDHSA VHSEQQVPTY IELTNSNRPA AIGSDSLSYS 180
  181 AAPQYPVSGL PGQDYNNSSV LQYATPNGAK PYRPWGAEMA Y

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.15
Match: 2j63A
Description: No description for 2j63A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle