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View Structure Prediction Details

Protein: scra-PA
Organism: Drosophila melanogaster
Length: 1212 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for scra-PA.

Description E-value Query
Range
Subject
Range
scra-PB - The gene scraps is referred to in FlyBase by the symbol Dmel\scra (CG2092, FBgn0261385). It is a pro...
623.0 [0..1] [1212..1]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPFTQHMLE KAEQRSRALG ISNASKFPLV ECSVPSSSAT SASGGDAGVL APRSRSPGGQ  60
   61 SAASGGGKVV TLGKATLEAS P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [82-318]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKPLRHYTAV NKENLDMGIE INITTDKPIG VQVEIQEQEV TDDEEQAEGG ALNPLLEAEP  60
   61 VNQPLARLRD TSRSRLQRMG ALYSNTDDLS SPIHRTEGQF HVTTGEEEDC GNRSSRQPKQ 120
  121 RLGKLAALAD TINQWEDDTS HHEVHRLLEA PPPKPHLSSR RAEKGPAPLP PKKDEVDEAS 180
  181 RTKQLKWDPK EEAAPASKVE DAVLTAKPPV PQKSTTVSQV AKNFASSAPA PKPAPAP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [319-378]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVSVKSGLVS GRAALFENKG TGGQSQGLRN QKDPCELSLK ERMKLFETGN NKAMLPMAPI  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [379-471]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSAPSITQIR AEEVKQHLAA MHPVTAAAAT TVVAATKPKQ ENKLRDKVAA LVANAQSSAE  60
   61 TRIKDIDRQR QEDMQIISNR FNKQKELFDN QPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [472-695]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSSVAAQARP PAPAPSRVVR PMPPPPPPPI AALSPGLASS KRRSPGDAPT TDEDSKRARK  60
   61 SHSDRLYPAL SDLDSSGDNC CAAETASATD DSHQQDEEET ESCMDESDDQ SQTEDSSAGM 120
  121 CNGSLGREIM SAVQRNEVEM QQQQTGKKTV RYADQDMYYD DSSLNSSQVS AGIDDYLDEA 180
  181 LVEDYGSTQD DQSDSGDEQN ASRLSLGSKG TTASNSFSFR KNPA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [696-911]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SICTPIEEHH EMEMDLQTPL LSGAQPVKSE LSVNQDNDNL VTLVHTVSFY RRQQSANSSN  60
   61 STPVRKICRE QQVMRSALAG DCHAKHRLEY DSPQQSDYVA AATDIADQTD EDDEEMQNAR 120
  121 EVNDASQAQD KIKKLLSEVC KQQQVIGQAS QALNLCAATV EFSGSTESVE GERYLLLATH 180
  181 RRQACLDEVQ RLRVENSIRP VGAPKEKGLL TVKDIT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [912-1024]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPLRQEYVRK MASNNINGHH LVCLLKYNEH VLATKTVPTM PGLLSVKFPD VLQLNNVYAD  60
   61 FRITLEIYGM LAQRDQLPHE LKYHINLNKK GGIKTPKKKG GENRLVMPPV QSP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1025-1212]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGPHVVRTPQ LVQYGFAIFS LREIQRTTWT LTQVLGVSPL EGVVHMKVNC ELSVSVEYKG  60
   61 FLTMFEDISG FGAWHRRWCY LNGSVINYWK YPDDEKRKTP MGSIDLNSCT SQKVTTAPRD 120
  121 ICARLNTMLL ECERPALETD QESLIIVPNG RTTTVRHLLS ADTKEEREEW CAYLNKALTL 180
  181 LRAWGTTH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.154902
Match: 1u27A
Description: Triglycine variant of the ARNO Pleckstrin Homology Domain in complex with Ins(1,3,4,5)P4
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle