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View Structure Prediction Details

Protein: p47-PA
Organism: Drosophila melanogaster
Length: 407 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for p47-PA.

Description E-value Query
Range
Subject
Range
NSF1C_CHICK - NSFL1 cofactor p47 OS=Gallus gallus GN=NSFL1C PE=2 SV=1
283.0 [0..1] [406..1]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAARGDLIAQ FIEITGTDEN VARFYLSSCD WDIEHALGNY WSTQADLPVP VPTVGHADNP  60
   61 KPKPTSSSGA SASASAAGAT KSADSAVATS SASVDIAP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [99-179]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AATKAKPKFA TLSDMSKESS SDDDQQAFYA GGSDRSGQQV LGPPKRKNFR EQLTDMMRSA  60
   61 QEQNIAEVGP STSSGSASGG S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [180-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGAVWGQGMR LGMTDNDHTA VGTKKPAATI ENKPVVVLKL WSQGFSIDGG ELRHYDDPQN  60
   61 KEFLETVMRG EIPQELLEMG RMVNVDVEDH RHEDF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1ss6A
Description: Solution structure of SEP domain from human p47
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [275-407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRQPVPQTFK GSGQKLGSPV ANLVTEAPTV PVALSPGEAA NQEASARDAI NLNSEAPSTT  60
   61 LQIRLADGSR LAAQFNLSHT VSDIRRFIQT ARPQYSTSNF ILVSSFPTRE LSDDNSTIEK 120
  121 AGLKNAALMQ RLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.09691
Match: 1s3sG
Description: Crystal structure of AAA ATPase p97/VCP ND1 in complex with p47 C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.2991525071751 bayes_pls_golite062009
protein binding 1.17286764835548 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle