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View Structure Prediction Details

Protein: pk-PC
Organism: Drosophila melanogaster
Length: 1299 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pk-PC.

Description E-value Query
Range
Subject
Range
gi|73948425 - gi|73948425|ref|XP_541659.2| PREDICTED: similar to zinc finger protein 91 (HPF7, HTF10) [Canis famil...
756.0 [0..346] [1140..343]

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Predicted Domain #1
Region A:
Residues: [1-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLSTGGGA GGSSGGPGGA DAAAAPAAGQ ATVTATGNME PAMVPRTANL LACKQWWRVC  60
   61 FLYGDQQKYY RQLYSKAAAQ RLADANQEPD NARDREYDTV DCDLIAGQLD AVEDADDGID 120
  121 LGDHSSTPKG GATTAGRPLF PHSSSPRRSK KLLRSLRAHV RGEKLPKNDT TTANESSEVT 180
  181 QRNARVTVLD DPFLFGIDAD HLGDLVVRGK 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [211-400]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RYSTLDATEN MARFYAEQEA TAQVLEIIEQ EEESPEQEAP KPALPPKQKQ QRPVPPLPPP  60
   61 PANRVTQDQG TQPAAPQVPL QPLTAGDLQF LNLSLRQRSL PRSMKPFKDA HDISFTFNEL 120
  121 DTSAEPEVAT GAAQQESNEP ISRTPLTQIS YLQKIPTLPR HFSPSGQGLA TPPALGSGGM 180
  181 GLPSSSSASA 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [401-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYAAQAAAGI LPTSPLPLQR HQQYLPPHHQ QHPGAGMGPG PGSGAAAGPP LGPQYSPGCS  60
   61 ANPKYSNAQL PPPPHHHHQL 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [481-558]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPALSTPSPP SLLHHPAGGT SSASAHAPFL GGPHMDMQRQ SHSDDDSGCA LEEYTWVPPG  60
   61 LRPDQVRLYF SQIPDDKV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.30103
Match: 1tf6A
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.26906680202757 bayes_pls_golite062009
nucleic acid binding 1.5361877165154 bayes_pls_golite062009
DNA binding 1.50805568602414 bayes_pls_golite062009
protein binding 0.905022998164426 bayes_pls_golite062009
transcription factor activity 0.594688838246446 bayes_pls_golite062009
signal transducer activity 0.0590340677124848 bayes_pls_golite062009
molecular transducer activity 0.0590340677124848 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [559-746]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYVNSPGEQY RVRQLLHQLP PHDNEVRYCH SLTDEERKEL RLFSTQRKRD ALGRGNVRQL  60
   61 MSARPCDGCD DLISTGDIAV FATRLGPNAS WHPACFACSV CRELLVDLIY FHRDGRMYCG 120
  121 RHHAETLKPR CSACDEIILA DECTEAEGRA WHMNHFACHE CDKQLGGQRY IMREGKPYCL 180
  181 HCFDAMFA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.0
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #6
Region A:
Residues: [747-826]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYCDYCGEAI GVDQGQMSHD GQHWHATDEC FSCNTCRCSL LGRAFLPRRG AIYCSIACSK  60
   61 GEPPTPSDSS GTGMYTTPTP 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.7
Match: 2cupA
Description: Solution structure of the Skeletal muscle LIM-protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.0300494058962 bayes_pls_golite062009
protein binding 1.20339329058617 bayes_pls_golite062009
receptor activity 1.00000843633623 bayes_pls_golite062009
transporter activity 0.893102092384062 bayes_pls_golite062009
signal transducer activity 0.73994900849782 bayes_pls_golite062009
molecular transducer activity 0.73994900849782 bayes_pls_golite062009
transmembrane transporter activity 0.7072042577999 bayes_pls_golite062009
substrate-specific transporter activity 0.489535882040485 bayes_pls_golite062009
DNA binding 0.397111874492592 bayes_pls_golite062009
nucleic acid binding 0.297808510495986 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.256518766904171 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [827-975]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTQRVRPHPQ APLPARIPSS HASSSPPMSP QQQQQHQATF NQAMYQMQSQ QMEAAGGLVD  60
   61 QSKSYAASDS DAGVVKDLEH GGHMGGGDLT DFSGGRASST SQNLSPLNSP GDFQPHFLPK 120
  121 PMELQRDGVY NFNEMSSNLD AAWSAKPTN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.154902
Match: 1ubdC
Description: Ying-yang 1 (yy1, zinc finger domain)
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [976-1087]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYHLQRQLLE NPHTASMPEL AGKLVAPPAH MQHLSQLHAV SSHQFQQHEY ADILHPPPPP  60
   61 PGEIPELPTP NLSVASTALP PELMGSPTHS AGDRSLNTPM STQSASHAPP HP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1088-1299]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSILSGASSS SPMSGEPAKK KGVRFEGIPD TLPRSRSYSG NGAGTSGGGE RERDRDKDKE  60
   61 GGGRHGHGHS SRRRRRRKSS SSSSHHRSGS GHRSHSTTRA DTYAPAQPLS SSYQGPPSVL 120
  121 QAANLVHESP SRQQRERERE REREESEESD VCSTCSSSSS SSEDYMMMYQ LPQRRHYGGV 180
  181 RVSYVPNDAL AYDRKRKPSE LGGDKDKNCI IS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle