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View Structure Prediction Details

Protein: Fmo-2-PA
Organism: Drosophila melanogaster
Length: 429 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Fmo-2-PA.

Description E-value Query
Range
Subject
Range
gi|114537206, gi... - gi|114707325|ref|ZP_01440222.1| dihydrolipoamide dehydrogenase [Fulvimarina pelagi HTCC2506], gi|114...
258.0 [0..1] [402..4]

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Predicted Domain #1
Region A:
Residues: [1-336]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKTSVDKRR VCVIGAGTAG LCALKNSLEA GLDAVAYERG TEIGGTWIFS EEMPKDEYDE  60
   61 VHSSMYEGLR TNLPKEVMGY PDYSYPDDIT ESFITSNQVL EFLRSYAEHF KLKAHIKLQH 120
  121 EVIRVRPRLD DWEVYVWDHS TDTCDPVYYD FVYVCNGHYT EPDLPEVEGL DLFEGNKMHS 180
  181 HLYRKADKFK DARVLIIGAG PSGMDITNHV RLAAKQVFLS HHLSTTPNTA FMGNVTQKPD 240
  241 VKRFTKDGAV FTDGSTESFD HVMFCTGYKY TFPCLSTDVG VQVIDNFVQP LWKHCININH 300
  301 PTMAFVGLPF NVIPTHIFDM QVRFTLKFFT GQRKFP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.39794
Match: 1vqwA
Description: Crystal structure of a protein with similarity to flavin-containing monooxygenases and to mammalian dimethylalanine monooxygenases
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 2.37832337019921 bayes_pls_golite062009
monooxygenase activity 1.9668697934131 bayes_pls_golite062009
catalytic activity 1.56773888754354 bayes_pls_golite062009
antioxidant activity 1.49429830917872 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 1.39990343076756 bayes_pls_golite062009
binding 0.439539948156364 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 0.160937050611661 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [337-429]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SREQMIADLE QEIGERWGCG VRNQKKAHQM GERQFVYYNE LASIAGIENI KPVIHKLMKD  60
   61 CGKKYIFELD TYRSNKYTIL DDENFLKNGE AIV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle