YRC Public Data Repository - Protein Structure Prediction

Protein:	CG10166-PA
Organism:	Drosophila melanogaster
Length:	241 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG10166-PA.

Description	E-value	Query Range	Subject Range
gi\|58391936, gi\|... - gi\|58391936\|ref\|XP_318984.2\| AGAP009866-PA [Anopheles gambiae str. PEST], gi\|55236087\|gb\|EAA14417.2\|... AGAP009866-PA - dolichol-phosphate mannosyltransferase\|protein_coding\|3R:44587243:44588145:-1\|gene:AGAP009866	193.0	[0..3]	[241..2]
gi\|50759086 - gi\|50759086\|ref\|XP_417511.1\| PREDICTED: similar to dolichol-phosphate-mannose synthase [Gallus gallu...	193.0	[0..7]	[241..8]
DPM1_MOUSE - Dolichol-phosphate mannosyltransferase subunit 1 OS=Mus musculus GN=Dpm1 PE=1 SV=1	192.0	[0..3]	[241..22]
gi\|187028529, gi... - gi\|39587882\|emb\|CAE67900.1\| Hypothetical protein CBG13497 [Caenorhabditis briggsae], gi\|187028529\|em... gi\|157759407 - gi\|157759407\|ref\|XP_001672047.1\| Hypothetical protein CBG13497 [Caenorhabditis briggsae AF16]	192.0	[0..3]	[238..1]
gi\|57525735, gi\|... - gi\|57525735\|ref\|NP_001003596.1\| dolichyl-phosphate mannosyltransferase 1 [Danio rerio], gi\|50418523\|...	191.0	[0..4]	[241..12]
gi\|72076181, gi\|... - gi\|72076181\|ref\|XP_793909.1\| PREDICTED: hypothetical protein [Strongylocentrotus purpuratus], gi\|115...	191.0	[0..1]	[241..1]
gi\|149042795, gi... - gi\|34860748\|ref\|XP_215949.2\| PREDICTED: similar to Dolichol-phosphate mannosyltransferase (Dolichol-...	190.0	[0..3]	[241..22]
gi\|54645637, gi\|... - gi\|54645637\|gb\|EAL34375.1\| GA10126 [Drosophila pseudoobscura pseudoobscura], gi\|125987087\|ref\|XP_001... gi\|125987087\|ref... - GA10126-PA [Drosophila pseudoobscura], GA10126 [Drosophila pseudoobscura pseudoobscura]	190.0	[0..1]	[241..1]
gi\|46329779 - gi\|46329779\|gb\|AAH68840.1\| LOC414689 protein [Xenopus laevis]	190.0	[0..7]	[241..31]

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Predicted Domain #1

Region A:
Residues: [1-241]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTNGHKYSI LMPTYNEKDN LPIIIWLIVK YMKASGLEYE VIVIDDGSPD GTLDVAKDLQ  60
   61 KIYGEDKIVL RPRGSKLGLG TAYIHGIKHA TGDFIVIIDA DLSHHPKFIP EFIKLQQEGN 120
  121 YDIVSGTRYA GNGGVFGWDF KRKLISRGAN FLSQVLLRPN ASDLTGSFRL YKKDVLEKCI 180
  181 ASCVSKGYVF QMEMLVRARQ HGYTIAEVPI TFVDRIYGTS KLGGTEIIQF AKNLLYLFAT 240
  241 T

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.154902
Match:	1xhbA
Description:	The Crystal Structure of UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase-T1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
mannosyltransferase activity	3.87594044828967	bayes_pls_golite062009
uridylyltransferase activity	2.78377598963895	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	2.70047942699289	bayes_pls_golite062009
UTP:glucose-1-phosphate uridylyltransferase activity	2.67542562955569	bayes_pls_golite062009
transferase activity	2.62166586999833	bayes_pls_golite062009
UDP-glycosyltransferase activity	2.33861720107822	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.01768771829228	bayes_pls_golite062009
nucleotidyltransferase activity	2.00651267140641	bayes_pls_golite062009
UTP-monosaccharide-1-phosphate uridylyltransferase activity	1.90086040617591	bayes_pls_golite062009
catalytic activity	1.88676710996045	bayes_pls_golite062009
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity	1.60323537823461	bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity	1.53617752123292	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	1.33788133706753	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	1.10309252319727	bayes_pls_golite062009
cytidylyltransferase activity	0.983416157001861	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.897978517422275	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.79629851874184	bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity	0.412018910498896	bayes_pls_golite062009
glucuronosyltransferase activity	0.287421645469793	bayes_pls_golite062009
mannose-phosphate guanylyltransferase activity	0.2363835251362	bayes_pls_golite062009
binding	0.074398891333042	bayes_pls_golite062009
acetylglucosaminyltransferase activity	0.0562130308868509	bayes_pls_golite062009
guanylyltransferase activity	0.0539392112504681	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: