YRC Public Data Repository - Protein Structure Prediction

Protein:	CG8360-PA, FBpp0...
Organism:	Drosophila melanogaster
Length:	158 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG8360-PA, FBpp0....

Description	E-value	Query Range	Subject Range
gi\|194106804, gi... - gi\|195147778\|ref\|XP_002014851.1\| GL18729 [Drosophila persimilis], gi\|194106804\|gb\|EDW28847.1\| GL1872... gi\|54644934, gi\|... - gi\|54644934\|gb\|EAL33674.1\| GA21017 [Drosophila pseudoobscura pseudoobscura], gi\|125985693\|ref\|XP_001... gi\|54644934\|gb\|E... - GA21017-PA [Drosophila pseudoobscura], GA21017 [Drosophila pseudoobscura pseudoobscura]	203.0	[0..1]	[153..1]
gi\|38492430, gi\|... - gi\|38492431\|pdb\|1MQ0\|B Chain B, Crystal Structure Of Human Cytidine Deaminase, gi\|38492430\|pdb\|1MQ0\|...	197.0	[0..22]	[158..6]
gi\|108998740 - gi\|108998740\|ref\|XP_001096632.1\| PREDICTED: similar to cytidine deaminase [Macaca mulatta]	197.0	[0..22]	[158..12]
gi\|41107631, gi\|... - gi\|45387777\|ref\|NP_991242.1\| cytidine deaminase [Danio rerio], gi\|41107631\|gb\|AAH65476.1\| Cytidine d...	192.0	[0..26]	[158..22]
gi\|76639480 - gi\|76639480\|ref\|XP_873476.1\| PREDICTED: similar to cytidine deaminase [Bos taurus]	189.0	[0..22]	[158..59]
CDD_MOUSE - Cytidine deaminase OS=Mus musculus GN=Cda PE=1 SV=2	189.0	[0..22]	[158..12]
gi\|109477553, gi... - gi\|34872207\|ref\|XP_342956.1\| PREDICTED: similar to cytidine deaminase [Rattus norvegicus], gi\|157822...	188.0	[0..22]	[158..12]

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Predicted Domain #1

Region A:
Residues: [1-158]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQVFINGAR DDLNVREFQS LDPSIQEIIL AATEARKQAY CPYSNFAVGA ALRTSDGTIY  60
   61 SGCNIENGAY ATCICAERTA AVKAISEGKR DFVACAVVAQ QDNGFTTPCG VCRQFLSEFV 120
  121 NGKDIPLYAA KPTNLPLRVL CTSVLQLLPN GFSFANGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.0
Match:	1mq0A
Description:	Crystal Structure of Human Cytidine Deaminase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cytidine deaminase activity	4.42667374679603	bayes_pls_golite062009
deaminase activity	2.76997916054448	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2.27736397496642	bayes_pls_golite062009
catalytic activity	1.70756445127105	bayes_pls_golite062009
binding	1.64474382695496	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.51294035758003	bayes_pls_golite062009
IMP cyclohydrolase activity	1.34771936728813	bayes_pls_golite062009
receptor binding	1.25331530291023	bayes_pls_golite062009
hydrolase activity	1.20889076546073	bayes_pls_golite062009
phosphoribosylaminoimidazolecarboxamide formyltransferase activity	1.06178740854563	bayes_pls_golite062009
nucleoside binding	0.66793245260795	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	0.36832789692523	bayes_pls_golite062009
cyclohydrolase activity	0.308525511259279	bayes_pls_golite062009
transition metal ion binding	0.25533482618887	bayes_pls_golite062009
protein binding	0.072557222523031	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	0.0520808212384716	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: