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View Structure Prediction Details

Protein: RFeSP-PA
Organism: Drosophila melanogaster
Length: 260 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RFeSP-PA.

Description E-value Query
Range
Subject
Range
RFeSP-PB, FBpp03... - The gene Rieske iron-sulfur protein is referred to in FlyBase by the symbol Dmel\RFeSP (CG7361, FBgn...
256.0 [0..1] [222..1]
gi|47155579, gi|... - gi|47155579|ref|NP_998251.1| ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 [Dan...
256.0 [0..5] [223..49]
UCRI_PONPY - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Pongo pygmaeus GN=UQCRFS1 PE=3 SV=1
254.0 [0..5] [224..50]
gi|45768728 - gi|45768728|gb|AAH67832.1| Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 [Homo ...
254.0 [0..5] [224..50]
gi|38674607 - gi|38674607|gb|AAR26321.1| Rieske iron sulfur protein/complex III subunit 9 precursor [Eulemur fulvu...
253.0 [0..5] [224..31]
UCRI_LAGLA - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Lagothrix lagotricha GN=UQCRFS1 PE=3 SV=1
253.0 [0..4] [224..49]
UCRI_SAISC - Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Saimiri sciureus GN=UQCRFS1 PE=3 SV=1
253.0 [0..4] [227..49]

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Predicted Domain #1
Region A:
Residues: [1-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMNAVSRAYV RGGAQVLSTG LKASGVAVNS MANRQAHTDL QVPDFSAYRR ESVKDSRRRN  60
   61 DTAEERKAFS YLMVGAGAVG GAYAAKGLVN TFIGSMSASA EVLAMAKIEI KLSDIPEGKS 120
  121 VTFKWRGKPL FIRHRTAAEI ETERNVPTST LRDPEADDVG TVEWVDSLML LPISSLATCD 180
  181 QARVAGGHRS VHASGLCAHR ERRRLGWLLL PLPRLPLRRL RKDPQGTRAP QLGGAHPRVP 240
  241 QRGSSRGRLE ELLSFKPPTA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.0
Match: 1bccE
Description: ISP subunit of the mitochondrial cytochrome bc1-complex, watersoluble domain; Iron-sulfur subunit (ISP) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane region
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquinol-cytochrome-c reductase activity 12.5243667017255 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor 12.5243667017255 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 9.125468664417 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 6.56410033542443 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 6.40889163290296 bayes_pls_golite062009
oxidoreductase activity 6.05060612159037 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 5.79350583896014 bayes_pls_golite062009
cation transmembrane transporter activity 5.52425708699797 bayes_pls_golite062009
ion transmembrane transporter activity 5.31511996363681 bayes_pls_golite062009
electron carrier activity 5.20213585732279 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.88364619884033 bayes_pls_golite062009
substrate-specific transporter activity 4.66567624087954 bayes_pls_golite062009
binding 1.1265044642485 bayes_pls_golite062009
catalytic activity 0.746741393172769 bayes_pls_golite062009
iron-sulfur cluster binding 0.71220774812099 bayes_pls_golite062009
metal cluster binding 0.71220774812099 bayes_pls_golite062009
protein binding 0.439276074643623 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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