YRC Public Data Repository - Protein Structure Prediction

Protein:	GBG8_RAT
Organism:	Rattus norvegicus
Length:	70 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GBG8_RAT.

Description	E-value	Query Range	Subject Range
gi\|84579919, gi\|... - gi\|84579919\|ref\|NP_034449.2\| guanine nucleotide binding protein (G protein), gamma 7 [Mus musculus],...	117.0	[0..1]	[69..1]
gi\|385168, gi\|21... - gi\|385168\|gb\|AAA65640.1\| G-protein gamma subunit, pir\|\|I56580 G-protein gamma subunit - rat, gi\|131...	115.0	[0..1]	[69..1]
tr\|G3V2N0\|G3V2N0... - Guanine nucleotide-binding protein subunit gamma OS=Homo sapiens GN=GNG2 PE=3 SV=1, Tax_Id=9606 Gene... gi\|114653023 - gi\|114653023\|ref\|XP_001158267.1\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]	114.0	[0..2]	[70..42]
gi\|50539862, gi\|... - gi\|50539862\|ref\|NP_001002397.1\| guanine nucleotide binding protein (G protein), gamma 7 [Danio rerio...	114.0	[0..2]	[69..1]
GNG7 - guanine nucleotide binding protein (G protein), gamma 7 gi\|109122851 - gi\|109122851\|ref\|XP_001098800.1\| PREDICTED: similar to guanine nucleotide binding protein (G protein... gi\|114674554 - gi\|114674554\|ref\|XP_001152049.1\| PREDICTED: guanine nucleotide binding protein (G protein), gamma 7 ... gi\|208968219 - gi\|208968219\|dbj\|BAG73948.1\| FLJ00058 [synthetic construct]	113.0	[0..2]	[69..1]
gi\|47229899 - gi\|47229899\|emb\|CAG10313.1\| unnamed protein product [Tetraodon nigroviridis]	113.0	[0..2]	[69..1]
gi\|62858615, gi\|... - gi\|89273841\|emb\|CAJ81829.1\| guanine nucleotide binding protein (G protein), gamma 7 [Xenopus tropica...	113.0	[0..2]	[69..1]

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Predicted Domain #1

Region A:
Residues: [1-70]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNNMAKIAE ARKTVEQLKL EVNIDRMKVS QAAAELLAFC ETHAKDDPLV TPVPAAENPF  60
   61 RDKRLFCTLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.30103
Match:	1xhmB
Description:	The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
GTPase activity	5.98519752009234	bayes_pls_golite062009
angiotensin receptor binding	3.57083467421742	bayes_pls_golite062009
type 1 angiotensin receptor binding	3.57083467421742	bayes_pls_golite062009
signal transducer activity	1.75801578312445	bayes_pls_golite062009
molecular transducer activity	1.75801578312445	bayes_pls_golite062009
binding	1.46430715205084	bayes_pls_golite062009
receptor binding	1.45302453757621	bayes_pls_golite062009
catalytic activity	0.467010875265274	bayes_pls_golite062009
protein binding	0.399162858691971	bayes_pls_golite062009
hydrolase activity	0.179751786037418	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: