YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|120603303, gi...
Organism:	Desulfovibrio vulgaris DP4
Length:	199 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|120603303, gi....

Description	E-value	Query Range	Subject Range
gi\|78357857, gi\|... - gi\|78357857\|ref\|YP_389306.1\| signal peptidase I [Desulfovibrio desulfuricans subsp. desulfuricans st...	3.0E-52	[3..199]	[24..220]
gi\|53758236, gi\|... - gi\|53804475\|ref\|YP_113922.1\| signal peptidase I [Methylococcus capsulatus str. Bath], gi\|53758236\|gb...	2.0E-51	[3..198]	[39..258]
gi\|85860052, gi\|... - gi\|85860052\|ref\|YP_462254.1\| signal peptidase I [Syntrophus aciditrophicus SB], gi\|85723143\|gb\|ABC78...	1.0E-50	[2..199]	[3..203]
gi\|68525801, gi\|... - gi\|94311356\|ref\|YP_584566.1\| signal peptidase I [Ralstonia metallidurans CH34], gi\|93355208\|gb\|ABF09...	2.0E-50	[3..189]	[69..295]
gi\|88790354, gi\|... - gi\|88812347\|ref\|ZP_01127597.1\| signal peptidase I [Nitrococcus mobilis Nb-231], gi\|88790354\|gb\|EAR21...	8.0E-50	[3..199]	[44..258]
LEP_PSEFL - Signal peptidase I OS=Pseudomonas fluorescens GN=lepB PE=3 SV=1	1.0E-49	[1..195]	[53..281]
gi\|88918906, gi\|... - gi\|88934448\|ref\|ZP_01140091.1\| Peptidase S26A, signal peptidase I [Geobacter uraniumreducens Rf4], g...	1.0E-49	[2..198]	[16..215]
LEP_PSEAE - Signal peptidase I OS=Pseudomonas aeruginosa GN=lepB PE=3 SV=1 LEP_PSEAE - Signal peptidase I OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) G... gi\|116048684, gi... - gi\|53727324\|ref\|ZP_00138365.2\| COG0681: Signal peptidase I [Pseudomonas aeruginosa UCBPP-PA14], gi\|1... gi\|218773517, gi... - gi\|218893289\|ref\|YP_002442158.1\| signal peptidase I [Pseudomonas aeruginosa LESB58], gi\|218773517\|em... gi\|107100229 - gi\|107100229\|ref\|ZP_01364147.1\| hypothetical protein PaerPA_01001252 [Pseudomonas aeruginosa PACS2]	1.0E-49	[1..199]	[53..284]
gi\|78363364, gi\|... - gi\|78485078\|ref\|YP_391003.1\| peptidase S26A, signal peptidase I [Thiomicrospira crunogena XCL-2], gi...	1.0E-49	[2..198]	[36..254]
gi\|116697047, gi... - gi\|71543954\|ref\|ZP_00665013.1\| Signal peptidase I [Syntrophobacter fumaroxidans MPOB], gi\|71489969\|g...	1.0E-49	[2..199]	[13..221]

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Predicted Domain #1

Region A:
Residues: [1-199]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQKNLLLEY IEALLVAFVL AMFIRTFVVQ AYKIPSGSML ETLQIGDHLL VNKFLYGVKI  60
   61 PFTHEYMIKG KDPKRGDIIV FEYPNNPSID YIKRIVGVPG DVIEVRDKQL YRNGEKVEES 120
  121 YIRHSEGDVV QPGVRDNYGP VTVPEGKYFA MGDNRDDSQD SRFWGFVDRT AIHGRAWIIY 180
  181 WSWEGLGNVR WERVGNVLH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.0
Match:	1t7dA
Description:	Crystal structure of Escherichia coli type I signal peptidase in complex with a lipopeptide inhibitor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	0.485843348899278	bayes_pls_golite062009
catalytic activity	0.415601732277814	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.237734983138449	bayes_pls_golite062009
hydrolase activity	0.188292586303013	bayes_pls_golite062009
protein binding	0.0579980138351139	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: