YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|123993147, gi...
Organism:	synthetic construct
Length:	249 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|123993147, gi....

Description	E-value	Query Range	Subject Range
gi\|109505678 - gi\|109505678\|ref\|XP_001064421.1\| PREDICTED: similar to triosephosphate isomerase [Rattus norvegicus]	0.0	[1..249]	[1..249]
gi\|55730014 - gi\|55730014\|emb\|CAH91732.1\| hypothetical protein [Pongo abelii] TPIS_PONAB - Triosephosphate isomerase OS=Pongo abelii GN=TPI1 PE=2 SV=1	0.0	[1..249]	[1..249]
TPIS_MACFA - Triosephosphate isomerase OS=Macaca fascicularis GN=TPI1 PE=2 SV=3 TPIS_MACMU - Triosephosphate isomerase OS=Macaca mulatta GN=TPI1 PE=3 SV=2	0.0	[1..249]	[1..249]
gi\|17389815 - gi\|17389815\|gb\|AAH17917.1\| Triosephosphate isomerase 1 [Homo sapiens]	0.0	[1..249]	[1..249]
gi\|83674984 - gi\|83674984\|gb\|ABC40672.1\| rcTPI1 [Gorilla gorilla] TPIS_GORGO - Triosephosphate isomerase OS=Gorilla gorilla gorilla GN=TPI1 PE=3 SV=1	0.0	[1..249]	[1..249]

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Predicted Domain #1

Region A:
Residues: [1-249]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPSRKFFVG GNWKMNGRKQ SLGELIGTLN AAKVPADTEV VCAPPTAYID FARQKLDPKI  60
   61 AVAAQNCYKV TNGAFTGEIS PGMIKDCGAT WVVLGHSERR HVFGESDELI GQKVAHALAE 120
  121 GLGVIACIGE KLDEREAGIT EKVVFEQTKV IADNVKDWSK VVLAYEPVWA IGTGKTATPQ 180
  181 QAQEVHEKLR GWLKSNVSDA VAQSTRIIYG GSVTGATCKE LASQPDVDGF LVGGASLKPE 240
  241 FVDIINAKQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	104.0
Match:	1r2rA
Description:	CRYSTAL STRUCTURE OF RABBIT MUSCLE TRIOSEPHOSPHATE ISOMERASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
triose-phosphate isomerase activity	5.94525596131351	bayes_pls_golite062009
intramolecular oxidoreductase activity	4.11751506069887	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	3.62219160185043	bayes_pls_golite062009
isomerase activity	2.06271139232842	bayes_pls_golite062009
binding	1.80264931081179	bayes_pls_golite062009
catalytic activity	1.7524198174984	bayes_pls_golite062009
protein binding	0.33788557654084	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: