YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|123993599, gi...
Organism:	synthetic construct
Length:	344 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|123993599, gi....

Description	E-value	Query Range	Subject Range
gi\|2135977, gi\|9... - gi\|998901\|gb\|AAB34865.1\| programmed cell death-2/Rp8 homolog [Homo sapiens], pir\|\|I52969 programmed ...	0.0	[1..344]	[1..344]
gi\|151555611 - gi\|151555611\|gb\|AAI48379.1\| Programmed cell death 2 [synthetic construct] gi\|26337749, gi\|... - gi\|26337749\|dbj\|BAC32560.1\| unnamed protein product [Mus musculus], gi\|148688511\|gb\|EDL20458.1\| prog...	0.0	[1..344]	[1..343]
PDCD2_RAT - Programmed cell death protein 2 OS=Rattus norvegicus GN=Pdcd2 PE=2 SV=2	0.0	[1..344]	[1..343]
gi\|109073365, gi... - gi\|109073367\|ref\|XP_001086513.1\| PREDICTED: similar to programmed cell death 2 isoform 1 isoform 9 [...	0.0	[1..344]	[1..344]
gi\|114610331 - gi\|114610331\|ref\|XP_520603.2\| PREDICTED: similar to programmed cell death 2 [Pan troglodytes]	0.0	[5..344]	[64..403]
PDCD2_BOVIN - Programmed cell death protein 2 OS=Bos taurus GN=PDCD2 PE=2 SV=1	0.0	[1..342]	[1..342]
gi\|73973832 - gi\|73973832\|ref\|XP_854542.1\| PREDICTED: similar to programmed cell death 2 isoform 1 isoform 2 [Cani...	0.0	[1..344]	[1..343]

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Predicted Domain #1

Region A:
Residues: [1-111]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAGARPVE LGFAESAPAW RLRSEQFPSK VGGRPAWLGA AGLPGPQALA CELCGRPLSF  60
   61 LLQVYAPLPG RPDAFHRCIF LFCCREQPCC AGLRVFRNQL PRKNDFYSYE P

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.07
Match:	1pv5A
Description:	Structure of Hypothetical Protein Ywqg from Bacillus subtilis
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [112-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSENPPPETG ESVCLQLKSG AHLCRVCGCL GPKTCSRCHK AYYCSKEHQT LDWRLGHKQA  60
   61 CAQPDHLDHI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.0
Match:	2dj8A
Description:	No description for 2dj8A was found.

Predicted functions:

Term	Confidence	Notes
binding	1.84945259695526	bayes_pls_golite062009
transcription regulator activity	0.545865021201494	bayes_pls_golite062009
protein binding	0.425029114798138	bayes_pls_golite062009
nucleic acid binding	0.411475115290625	bayes_pls_golite062009
DNA binding	0.354211088524398	bayes_pls_golite062009
transcription activator activity	0.24422052145333	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [182-344]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPDHNFLFPE FEIVIETEDE IMPEVVEKED YSEIIGSMGE ALEEELDSMA KHESREDKIF  60
   61 QKFKTQIALE PEQILRYGRG IAPIWISGEN IPQEKDIPDC PCGAKRILEF QVMPQLLNYL 120
  121 KADRLGKSID WGILAVFTCA ESCSLGTGYT EEFVWKQDVT DTP

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	119.244125
Match:	PF04194.4
Description:	No description for PF04194.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: