YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|121547259, gi...
Organism:	Vibrio cholerae 2740-80
Length:	236 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|121547259, gi....

Description	E-value	Query Range	Subject Range
gi\|83574855, gi\|... - gi\|83591941\|ref\|YP_425693.1\| phosphate uptake regulator, PhoU [Rhodospirillum rubrum ATCC 11170], gi... gi\|48763369 - ref\|ZP_00267924.1\| COG0704: Phosphate uptake regulator [Rhodospirillum rubrum]	218.0	[0..5]	[229..4]
gi\|77977952, gi\|... - gi\|77977952\|ref\|ZP_00833389.1\| COG0704: Phosphate uptake regulator [Yersinia intermedia ATCC 29909],...	213.0	[0..1]	[235..4]
gi\|166205645, gi... - gi\|166213347\|ref\|ZP_02239382.1\| phosphate transport system regulatory protein PhoU [Yersinia pestis ... gi\|167401532, gi... - gi\|167401532\|ref\|ZP_02307026.1\| phosphate transport system regulatory protein PhoU [Yersinia pestis ... gi\|167425542, gi... - gi\|167425542\|ref\|ZP_02317295.1\| phosphate transport system regulatory protein PhoU [Yersinia pestis ... gi\|145601160, gi... - gi\|145601160\|ref\|YP_001165236.1\| transcriptional regulator PhoU [Yersinia pestis Pestoides F], gi\|14... gi\|186897478, gi... - gi\|186897478\|ref\|YP_001874590.1\| transcriptional regulator PhoU [Yersinia pseudotuberculosis PB1/+],... gi\|108782061, gi... - gi\|108810148\|ref\|YP_654064.1\| transcriptional regulator PhoU [Yersinia pestis Antiqua], gi\|108782061... Q663R6\|Q663R6_YERPS - Phosphate transport regulatory protein - Yersinia pseudotuberculosis gi\|51591525, gi\|... - gi\|51598243\|ref\|YP_072434.1\| transcriptional regulator PhoU [Yersinia pseudotuberculosis IP 32953], ... gi\|108814130, gi... - gi\|229904671\|ref\|ZP_04519782.1\| negative regulator of PhoR/PhoB two-component regulator [Yersinia pe... gi\|45443743, gi\|... - gi\|45443743\|ref\|NP_995282.1\| transcriptional regulator PhoU [Yersinia pestis biovar Microtus str. 91... gi\|22127995, gi\|... - gi\|22127995\|ref\|NP_671418.1\| transcriptional regulator PhoU [Yersinia pestis KIM], gi\|21961142\|gb\|AA... gi\|162419718, gi... - gi\|77634101\|ref\|ZP_00796209.1\| COG0704: Phosphate uptake regulator [Yersinia pestis Angola], gi\|1624... gi\|152962140, gi... - gi\|77630946\|ref\|ZP_00793532.1\| COG0704: Phosphate uptake regulator [Yersinia pseudotuberculosis IP 3... gi\|229700221, gi... - gi\|229896783\|ref\|ZP_04511946.1\| negative regulator of PhoR/PhoB two-component regulator [Yersinia pe...	211.0	[0..1]	[231..4]
gi\|67845242 - gi\|67845242\|emb\|CAH41987.1\| phosphate regulon repressor protein [Erwinia amylovora]	211.0	[0..1]	[231..4]
gi\|77961808, gi\|... - gi\|77961808\|ref\|ZP_00825638.1\| COG0704: Phosphate uptake regulator [Yersinia mollaretii ATCC 43969],...	211.0	[0..1]	[235..4]
gi\|238724196, gi... - gi\|77973792\|ref\|ZP_00829337.1\| COG0704: Phosphate uptake regulator [Yersinia frederiksenii ATCC 3364...	211.0	[0..1]	[235..4]
gi\|77958177, gi\|... - gi\|77958177\|ref\|ZP_00822215.1\| COG0704: Phosphate uptake regulator [Yersinia bercovieri ATCC 43970],...	211.0	[0..1]	[231..4]
gi\|62182337, gi\|... - gi\|62182337\|ref\|YP_218754.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ser... gi\|56415723, gi\|... - gi\|56415723\|ref\|YP_152798.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ser... lcl\|NC_016856.1_... - [gene=phoU] [protein=transcriptional regulator PhoU] [protein_id=YP_005240120.1] [location=complemen... gi\|205331632, gi... - gi\|205331632\|gb\|EDZ18396.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|168242073, gi... - gi\|205339007\|gb\|EDZ25771.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|205350224, gi... - gi\|205350224\|gb\|EDZ36855.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|195632487, gi... - gi\|195632487\|gb\|EDX50971.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|161366336, gi... - gi\|161616972\|ref\|YP_001590937.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica... gi\|205325569, gi... - gi\|205325569\|gb\|EDZ13408.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|206710879, gi... - gi\|207859076\|ref\|YP_002245727.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica... gi\|213052684 - gi\|213052684\|ref\|ZP_03345562.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ... gi\|16762476 - gi\|16762476\|ref\|NP_458093.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ser... gi\|214001311 - gi\|214001311\|ref\|ZP_03412046.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ... gi\|224470177, gi... - gi\|224585649\|ref\|YP_002639448.1\| phosphate transport system regulatory protein [Salmonella enterica ... gi\|197939343, gi... - gi\|198244827\|ref\|YP_002217799.1\| phosphate transport system regulatory protein PhoU [Salmonella ente... gi\|200388264, gi... - gi\|200388264\|ref\|ZP_03214876.1\| phosphate transport system regulatory protein PhoU [Salmonella enter... gi\|204928454, gi... - gi\|204928454\|ref\|ZP_03219653.1\| phosphate transport system regulatory protein PhoU [Salmonella enter... gi\|205354563, gi... - gi\|205354563\|ref\|YP_002228364.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica... gi\|194712421, gi... - gi\|194736919\|ref\|YP_002116793.1\| phosphate transport system regulatory protein PhoU [Salmonella ente... gi\|197251471, gi... - gi\|197251471\|ref\|YP_002148788.1\| phosphate transport system regulatory protein PhoU [Salmonella ente... gi\|197264784, gi... - gi\|197264784\|ref\|ZP_03164858.1\| phosphate transport system regulatory protein PhoU [Salmonella enter... gi\|197364651, gi... - gi\|197364651\|ref\|YP_002144288.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica... gi\|205340502, gi... - gi\|205340502\|gb\|EDZ27266.1\| phosphate transport system regulatory protein PhoU [Salmonella enterica ... gi\|194404265, gi... - gi\|194445602\|ref\|YP_002043099.1\| phosphate transport system regulatory protein PhoU [Salmonella ente... gi\|194451489, gi... - gi\|194451489\|ref\|YP_002047882.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica... gi\|194457668, gi... - gi\|194471304\|ref\|ZP_03077288.1\| phosphate transport system regulatory protein PhoU [Salmonella enter... gi\|16422426, gi\|... - gi\|16767137\|ref\|NP_462752.1\| transcriptional regulator PhoU [Salmonella typhimurium LT2], gi\|1642242... gi\|29143964, gi\|... - gi\|29143964\|ref\|NP_807306.1\| transcriptional regulator PhoU [Salmonella enterica subsp. enterica ser... gi\|16504781, gi\|... - gi\|25300313\|pir\|\|AF0956 phosphate transport system regulatory protein STY3930 [imported] - Salmonell...	211.0	[0..1]	[231..4]
gi\|15982002, gi\|... - gi\|218931089\|ref\|YP_002348964.1\| transcriptional regulator PhoU [Yersinia pestis CO92], gi\|16124221\|... gi\|25300312 - pir\|\|AE0499 probable phosphate transport system protein phoU [imported] - Yersinia pestis (strain CO... gi\|229839821, gi... - gi\|229839821\|ref\|ZP_04459980.1\| negative regulator of PhoR/PhoB two-component regulator [Yersinia pe... gi\|229841906, gi... - gi\|229841906\|ref\|ZP_04462062.1\| negative regulator of PhoR/PhoB two-component regulator [Yersinia pe... gi\|89104500, gi\|... - gi\|89104500\|ref\|ZP_01177041.1\| COG0704: Phosphate uptake regulator [Yersinia pestis biovar Orientali... gi\|165991498, gi... - gi\|166009576\|ref\|ZP_02230474.1\| phosphate transport system regulatory protein PhoU [Yersinia pestis ... gi\|165926131, gi... - gi\|165926131\|ref\|ZP_02221963.1\| phosphate transport system regulatory protein PhoU [Yersinia pestis ... gi\|167468124 - gi\|167468124\|ref\|ZP_02332828.1\| transcriptional regulator PhoU [Yersinia pestis FV-1] gi\|166958252, gi... - gi\|167422860\|ref\|ZP_02314613.1\| phosphate transport system regulatory protein PhoU [Yersinia pestis ... gi\|150260953, gi... - gi\|150260953\|ref\|ZP_01917681.1\| putative phosphate transport system protein [Yersinia pestis CA88-41...	210.0	[0..1]	[231..4]
tr\|E4RDX8\|E4RDX8... - Phosphate-specific transport system accessory protein PhoU OS=Pseudomonas putida (strain BIRD-1) GN=... gi\|148550433, gi... - gi\|82739702\|ref\|ZP_00902494.1\| PhoU [Pseudomonas putida F1], gi\|82713229\|gb\|EAP48351.1\| PhoU [Pseudo... tr\|I7CD45\|I7CD45... - Phosphate-specific transport system accessory protein PhoU OS=Pseudomonas putida (strain DOT-T1E) GN... gi\|24987134, gi\|... - gi\|26992001\|ref\|NP_747426.1\| phosphate transporter PhoU [Pseudomonas putida KT2440], gi\|24987134\|gb\|...	210.0	[0..3]	[236..7]

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Predicted Domain #1

Region A:
Residues: [1-236]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQFGRHISGQ FNVELESIRS QVLTMGGLVE QQLTLAMQAL HEDDEKLARR VIADDHKVNA  60
   61 MEVSIDEACT RIIAKRQPTA KDLRLIMAII KTITDLERIG DSATKMAYIA IERPPAKQHQ 120
  121 FQVSLEPLCR QAIAMLHQVL DAFARMDVEA AAEIYKQDDR LDKEYEAVVR QLMTYMMEDP 180
  181 KNIPHILQVI WSARAIERVG DRCQNICEYI IYFVKGKDVR HLGDQGIDDV LKKPSL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.09691
Match:	1t72A
Description:	Crystal structure of phosphate transport system protein phoU from Aquifex aeolicus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.52706367695557	bayes_pls_golite062009
nucleic acid binding	1.40207651011289	bayes_pls_golite062009
DNA binding	1.39485368870356	bayes_pls_golite062009
transcription factor activity	1.27583598395229	bayes_pls_golite062009
binding	0.775039544296942	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: