YRC Public Data Repository - Protein Structure Prediction

Protein:	MIF_RAT
Organism:	Rattus norvegicus
Length:	115 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIF_RAT.

Description	E-value	Query Range	Subject Range
MIF_BOVIN - Macrophage migration inhibitory factor OS=Bos taurus GN=MIF PE=1 SV=6 MIF_SHEEP - Macrophage migration inhibitory factor OS=Ovis aries GN=MIF PE=3 SV=1	186.0	[0..1]	[115..1]
gi\|694108 - gi\|694108\|gb\|AAA62644.1\| macrophage migration inhibitory factor	186.0	[0..1]	[115..1]
MIF_MOUSE - Macrophage migration inhibitory factor OS=Mus musculus GN=Mif PE=1 SV=2	185.0	[0..1]	[115..1]
gi\|49659870, gi\|... - gi\|50881974\|gb\|AAT85562.1\| BS011P [Gekko japonicus], gi\|49659870\|gb\|AAT68234.1\| GekBS032P [Gekko jap... MIF_PIG - Macrophage migration inhibitory factor OS=Sus scrofa GN=MIF PE=1 SV=3	185.0	[0..1]	[115..1]
MIF_MERUN - Macrophage migration inhibitory factor OS=Meriones unguiculatus GN=MIF PE=3 SV=3	185.0	[0..1]	[115..1]
gi\|30585217, gi\|... - gi\|61365201\|gb\|AAX42670.1\| macrophage migration inhibitory factor [synthetic construct], gi\|60825453...	184.0	[0..1]	[115..1]
MIF - macrophage migration inhibitory factor (glycosylation-inhibiting factor) HGNC:7097\|MIM:15... - migration inhibitory factor (glycosylation-inhibiting factor) MIF_MACMU - Macrophage migration inhibitory factor OS=Macaca mulatta GN=MIF PE=3 SV=4 MIF_MACFA - Macrophage migration inhibitory factor OS=Macaca fascicularis GN=MIF PE=3 SV=3 gi\|61355068, gi\|... - gi\|61355068\|gb\|AAX41096.1\| macrophage migration inhibitory factor [synthetic construct], gi\|60813284...	183.0	[0..1]	[115..1]

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Predicted Domain #1

Region A:
Residues: [1-115]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPMFIVNTNV PRASVPEGFL SELTQQLAQA TGKPAQYIAV HVVPDQLMTF SGTSDPCALC  60
   61 SLHSIGKIGG AQNRNYSKLL CGLLSDRLHI SPDRVYINYY DMNAANVGWN GSTFA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.045757
Match:	1gifA
Description:	Microphage migration inhibition factor (MIF)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phenylpyruvate tautomerase activity	3.84932786282501	bayes_pls_golite062009
cytokine activity	2.80410252537768	bayes_pls_golite062009
intramolecular oxidoreductase activity	2.17252244354636	bayes_pls_golite062009
binding	1.9717928129965	bayes_pls_golite062009
receptor binding	1.79096938850925	bayes_pls_golite062009
protein binding	1.70051621352839	bayes_pls_golite062009
catalytic activity	0.836951613125537	bayes_pls_golite062009
isomerase activity	0.804529932513639	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing C=C bonds	0.452407074010503	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: