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View Structure Prediction Details

Protein: PA2GA_MOUSE
Organism: Mus musculus
Length: 146 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PA2GA_MOUSE.

Description E-value Query
Range		 Subject
Range
PA2BB_GLOHA - Basic phospholipase A2 B OS=Gloydius halys PE=1 SV=2
 177.0 [0..1] [146..1]
PA23_ECHCO - Phospholipase A2 EC3 OS=Echis coloratus PE=3 SV=1
 177.0 [0..1] [146..1]
PA2BW_PROFL - Basic phospholipase A2 PL-X' OS=Protobothrops flavoviridis PE=2 SV=1
 176.0 [0..1] [146..1]
PA2B_BOTSC - Basic phospholipase A2 Bs-N6 OS=Bothriechis schlegelii PE=1 SV=1
 175.0 [0..1] [146..1]
PA2B2_SISCT - Basic phospholipase A2 Sct-N6 OS=Sistrurus catenatus tergeminus PE=2 SV=1
 175.0 [0..1] [146..1]
gi|76676926 - gi|76676926|ref|XP_582666.2| PREDICTED: similar to Group IIE secretory phospholipase A2 precursor (P...
 175.0 [0..21] [146..312]
gi|50874498, gi|... - gi|50874498|emb|CAE47238.1| ammodytin I2(C) isoform [Vipera ammodytes meridionalis], gi|50874494|emb...
gi|50874510, gi|... - gi|50874516|emb|CAE47247.1| ammodytin I2(C) isoform [Vipera ammodytes montandoni], gi|50874514|emb|C...
 175.0 [0..1] [146..1]
PA2GA_RAT - Phospholipase A2, membrane associated OS=Rattus norvegicus GN=Pla2g2a PE=1 SV=2
 174.0 [0..1] [146..1]
PA2B_VIPBB - Basic phospholipase A2 Pla2Vb OS=Vipera berus berus PE=1 SV=2
 174.0 [0..1] [146..1]

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Predicted Domain #1
Region A:
Residues: [1-146] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVLLLLAAS IMAFGSIQVQ GNIAQFGEMI RLKTGKRAEL SYAFYGCHCG LGGKGSPKDA  60
   61 TDRCCVTHDC CYKSLEKSGC GTKLLKYKYS HQGGQITCSA NQNSCQKRLC QCDKAAAECF 120
  121 ARNKKTYSLK YQFYPNMFCK GKKPKC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.0
Match: 1aypA
Description: Phospholipase A2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phospholipase A2 activity 5.6430968678228 bayes_pls_golite062009
phospholipase activity 5.38445724291842 bayes_pls_golite062009
calcium-dependent phospholipase A2 activity 4.05813159633475 bayes_pls_golite062009
lipase activity 3.51338748073942 bayes_pls_golite062009
cell surface binding 3.03976629465117 bayes_pls_golite062009
carboxylesterase activity 2.68079964970429 bayes_pls_golite062009
receptor binding 2.23831898285432 bayes_pls_golite062009
binding 1.6033670102211 bayes_pls_golite062009
protein binding 1.47445022237761 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.42015803437458 bayes_pls_golite062009
hydrolase activity 1.32355620269997 bayes_pls_golite062009
heparin binding 1.06811660027805 bayes_pls_golite062009
catalytic activity 0.975181414554529 bayes_pls_golite062009
glycosaminoglycan binding 0.453108206649759 bayes_pls_golite062009
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