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View Structure Prediction Details

Protein: CXL15_MOUSE
Organism: Mus musculus
Length: 167 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CXL15_MOUSE.

Description E-value Query
Range
Subject
Range
gi|74198942, gi|... - gi|74198942|dbj|BAE30690.1| unnamed protein product [Mus musculus], gi|74142494|dbj|BAE31998.1| unna...
124.0 [0..1] [130..1]
gi|55531 - gi|55531|emb|CAA34901.1| JE product [Rattus sp.]
CCL2_RAT - C-C motif chemokine 2 OS=Rattus norvegicus GN=Ccl2 PE=2 SV=1
123.0 [0..1] [130..1]
gi|27228299 - gi|27228299|gb|AAN85636.1| monocyte chemoattractant protein-1 [Sigmodon hispidus]
122.0 [0..1] [134..1]
gi|1082968 - pir||A53096 interleukin-8 precursor - pig
IL8_PIG - Interleukin-8 OS=Sus scrofa GN=CXCL8 PE=1 SV=1
110.0 [0..5] [99..10]
gi|21070221, gi|... - gi|21070221|gb|AAM34214.1|AF506972_1 mcp-2 [Equus caballus], gi|126352332|ref|NP_001075333.1| mcp-2 ...
108.0 [0..1] [97..1]
CCL4_CHICK - C-C motif chemokine 4 homolog OS=Gallus gallus GN=CCL4 PE=3 SV=4
108.0 [0..1] [88..1]

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Predicted Domain #1
Region A:
Residues: [1-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAQGWSMLL LAVLNLGIFV RPCDTQELRC LCIQEHSEFI PLKLIKNIMV IFETIYCNRK  60
   61 EVIAVPKNGS MICLDPDAPW VKATVGPITN RFLPEDLKQK EFPPAMKLLY SVEHEKPLYL 120
  121 SFGRPENKRI FPFPIRETSR HFADLAHNSD RNFLRDSSEV SLTGSDA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.221849
Match: 1bo0A
Description: MONOCYTE CHEMOATTRACTANT PROTEIN-3, NMR, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytokine activity 7.36696853209356 bayes_pls_golite062009
chemokine activity 7.19574940007631 bayes_pls_golite062009
chemokine receptor binding 7.19574940007631 bayes_pls_golite062009
G-protein-coupled receptor binding 6.50180912315564 bayes_pls_golite062009
receptor binding 5.07536698514309 bayes_pls_golite062009
interleukin-8 receptor binding 3.11139680462527 bayes_pls_golite062009
chemoattractant activity 3.05299139114464 bayes_pls_golite062009
binding 2.74508851001995 bayes_pls_golite062009
protein binding 2.67868500877972 bayes_pls_golite062009
heparin binding 2.14306964280471 bayes_pls_golite062009
pattern binding 1.02739535268516 bayes_pls_golite062009
glycosaminoglycan binding 1.02635112283657 bayes_pls_golite062009
polysaccharide binding 0.8745248884958 bayes_pls_golite062009
carbohydrate binding 0.49941396747283 bayes_pls_golite062009
CCR chemokine receptor binding 0.0691884426876317 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle