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View Structure Prediction Details

Protein: gi|31981282, gi|...
Organism: Mus musculus
Length: 184 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|31981282, gi|....

Description E-value Query
Range
Subject
Range
LGUL_RAT - Lactoylglutathione lyase OS=Rattus norvegicus GN=Glo1 PE=1 SV=3
183.0 [0..1] [184..1]
LGUL_MOUSE - Lactoylglutathione lyase OS=Mus musculus GN=Glo1 PE=1 SV=3
183.0 [0..1] [184..1]
gi|114607262 - gi|114607262|ref|XP_001173775.1| PREDICTED: glyoxalase I isoform 5 [Pan troglodytes]
182.0 [0..1] [184..1]
gi|62089188 - gi|62089188|dbj|BAD93038.1| glyoxalase I variant [Homo sapiens]
182.0 [0..1] [184..5]
LGUL_MACFA - Lactoylglutathione lyase OS=Macaca fascicularis GN=GLO1 PE=2 SV=3
gi|109071018 - gi|109071018|ref|XP_001117098.1| PREDICTED: glyoxalase I [Macaca mulatta]
182.0 [0..1] [184..1]
gi|61367882, gi|... - gi|61367890|gb|AAX43062.1| glyoxalase I [synthetic construct], gi|61367882|gb|AAX43061.1| glyoxalase...
181.0 [0..1] [184..1]

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Predicted Domain #1
Region A:
Residues: [1-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPQPASSG LTDETAFSCC SDPDPSTKDF LLQQTMLRIK DPKKSLDFYT RVLGLTLLQK  60
   61 LDFPAMKFSL YFLAYEDKND IPKDKSEKTA WMFSRKATLE LTHNWGTEDD ETQSYHNGNS 120
  121 DPRGFGHIGI AVPDVYSACK RFEELGVKFV KKPDDGKMKG LAFIQDPDGY WIEILNPNKI 180
  181 ATII

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.045757
Match: 1froA
Description: Glyoxalase I (lactoylglutathione lyase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
lactoylglutathione lyase activity 3.91334658149719 bayes_pls_golite062009
carbon-sulfur lyase activity 1.44168339433372 bayes_pls_golite062009
catalytic activity 1.21778090213032 bayes_pls_golite062009
binding 1.0454158969791 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 0.397354910065381 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 0.343093696737896 bayes_pls_golite062009
protein binding 0.28912087714501 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle