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View Structure Prediction Details

Protein: ST2A2_MOUSE
Organism: Mus musculus
Length: 285 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ST2A2_MOUSE.

Description E-value Query
Range
Subject
Range
SUH2_RAT - Probable alcohol sulfotransferase OS=Rattus norvegicus PE=2 SV=2
gi|116138260, gi... - gi|116138655|gb|AAI25368.1| RIKEN cDNA C730007P19 gene [Mus musculus], gi|116138260|gb|AAI25366.1| R...
264.0 [0..1] [285..1]
gi|1091605 - gi|1091605|prf||2021282B sulfotransferase:ISOTYPE=a1
263.0 [0..1] [285..1]
gi|76629434 - gi|76629434|ref|XP_602209.2| PREDICTED: similar to Sulfotransferase K1 (rSULT1C2) [Bos taurus]
260.0 [0..2] [281..72]
gi|114661984 - gi|114661984|ref|XP_001151415.1| PREDICTED: similar to aryl sulfotransferase isoform 5 [Pan troglody...
256.0 [0..2] [281..64]

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Predicted Domain #1
Region A:
Residues: [1-285]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSDYNWFEG IPFPAISYQR EILEDIRNKF VVKEEDLLIL TYPKSGTNWL NEIVCLIQTK  60
   61 GDPKWIQTVP IWDRSPWIET EIGYSAIINK EGPRLITSHL PIHLFSKSFF SSKAKAIYLM 120
  121 RNPRDILVSG YFFWGNTNLV KNPGSLGTYF EWFLQGNVLF GSWFEHVRGW LSMREWDNFL 180
  181 VLYYEDMKKD TKGTIKKICD FLGKNLGPDE LDLVLKYSSF QAMKENNMSN YSLIKEDRVT 240
  241 NGLKLMRKGT TGDWKNHFTV AQAEAFDKVF QEKMAGFPPG MFPWE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.09691
Match: 1j99A
Description: Hydroxysteroid sulfotransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.01755875920323 bayes_pls_golite062009
motor activity 1.56647300556411 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
microfilament motor activity 0.48896543101005 bayes_pls_golite062009
nucleotide binding 0.294629388587597 bayes_pls_golite062009
purine nucleotide binding 0.258527744324945 bayes_pls_golite062009
pyrophosphatase activity 0.219555040684154 bayes_pls_golite062009
purine ribonucleotide binding 0.218726793699558 bayes_pls_golite062009
ribonucleotide binding 0.21867107119713 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.198256709027213 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.197994873032963 bayes_pls_golite062009
cytoskeletal protein binding 0.145265867076169 bayes_pls_golite062009
protein binding 0.071010918255742 bayes_pls_golite062009
nucleic acid binding 0.065286528593603 bayes_pls_golite062009
DNA-dependent ATPase activity 0.0518105987344697 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle