YRC Public Data Repository - Protein Structure Prediction

Protein:	HXB8_MOUSE
Organism:	Mus musculus
Length:	243 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXB8_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|109114201 - gi\|109114201\|ref\|XP_001088929.1\| PREDICTED: similar to homeobox B8 isoform 1 [Macaca mulatta] HOXB8 - homeobox B8 HGNC:5119\|MIM:14... - B8, B8 gi\|146327438, gi... - gi\|208966500\|dbj\|BAG73264.1\| homeobox B8 [synthetic construct], gi\|146327438\|gb\|AAI41561.1\| Homeobox... ENSCJAT00000014593 - null	170.0	[0..1]	[243..1]
gi\|57091665 - gi\|57091665\|ref\|XP_548179.1\| PREDICTED: similar to homeo box B8 [Canis familiaris]	170.0	[0..1]	[243..1]
gi\|109491742 - gi\|109491742\|ref\|XP_001081339.1\| PREDICTED: similar to Homeobox protein Hox-B9 (Hox-2.5) [Rattus nor...	165.0	[0..1]	[243..442]
gi\|109114199 - gi\|109114199\|ref\|XP_001089161.1\| PREDICTED: similar to homeobox B9 isoform 3 [Macaca mulatta]	160.0	[0..1]	[243..305]
HXB8A_DANRE - Homeobox protein Hox-B8a OS=Danio rerio GN=hoxb8a PE=2 SV=1	159.0	[0..1]	[242..1]
gi\|45382501, gi\|... - gi\|45382501\|ref\|NP_990242.1\| homeo box B8 [Gallus gallus], gi\|4099016\|gb\|AAD09228.1\| Hoxb-8 [Gallus ...	157.0	[0..1]	[243..1]
HXB8A_TAKRU - Homeobox protein Hox-B8a OS=Takifugu rubripes GN=hoxb8a PE=3 SV=1	143.0	[0..1]	[220..1]

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Predicted Domain #1

Region A:
Residues: [1-144]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSYFVNSLF SKYKTGESLR PNYYDCGFAQ DLGGRPTVVY GPSSGGSFQH PSQIQEFYHG  60
   61 PSSLSTAPYQ QNPCAVACHG DPGNFYGYDP LQRQSLFGAQ DPDLVQYADC KLAAASGLGE 120
  121 EAEGSEQSPS PTQLFPWMRP QAAA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [145-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRRRGRQTYS RYQTLELEKE FLFNPYLTRK RRIEVSHALG LTERQVKIWF QNRRMKWKKE  60
   61 NNKDKFPSSK CEQEELEKEK LERAPETAEQ GDAQKGDKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.0
Match:	1homA
Description:	DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits