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View Structure Prediction Details

Protein: HXB8_MOUSE
Organism: Mus musculus
Length: 243 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HXB8_MOUSE.

Description E-value Query
Range
Subject
Range
gi|109114201 - gi|109114201|ref|XP_001088929.1| PREDICTED: similar to homeobox B8 isoform 1 [Macaca mulatta]
HOXB8 - homeobox B8
HGNC:5119|MIM:14... - B8, B8
gi|146327438, gi... - gi|208966500|dbj|BAG73264.1| homeobox B8 [synthetic construct], gi|146327438|gb|AAI41561.1| Homeobox...
ENSCJAT00000014593 - null
170.0 [0..1] [243..1]
gi|57091665 - gi|57091665|ref|XP_548179.1| PREDICTED: similar to homeo box B8 [Canis familiaris]
170.0 [0..1] [243..1]
gi|109491742 - gi|109491742|ref|XP_001081339.1| PREDICTED: similar to Homeobox protein Hox-B9 (Hox-2.5) [Rattus nor...
165.0 [0..1] [243..442]
gi|109114199 - gi|109114199|ref|XP_001089161.1| PREDICTED: similar to homeobox B9 isoform 3 [Macaca mulatta]
160.0 [0..1] [243..305]
HXB8A_DANRE - Homeobox protein Hox-B8a OS=Danio rerio GN=hoxb8a PE=2 SV=1
159.0 [0..1] [242..1]
gi|45382501, gi|... - gi|45382501|ref|NP_990242.1| homeo box B8 [Gallus gallus], gi|4099016|gb|AAD09228.1| Hoxb-8 [Gallus ...
157.0 [0..1] [243..1]
HXB8A_TAKRU - Homeobox protein Hox-B8a OS=Takifugu rubripes GN=hoxb8a PE=3 SV=1
143.0 [0..1] [220..1]

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Predicted Domain #1
Region A:
Residues: [1-144]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSYFVNSLF SKYKTGESLR PNYYDCGFAQ DLGGRPTVVY GPSSGGSFQH PSQIQEFYHG  60
   61 PSSLSTAPYQ QNPCAVACHG DPGNFYGYDP LQRQSLFGAQ DPDLVQYADC KLAAASGLGE 120
  121 EAEGSEQSPS PTQLFPWMRP QAAA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.258 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.258 N/A N/A a.60.2 RuvA domain 2-like
View Download 0.232 N/A N/A d.109.1 Actin depolymerizing proteins

Predicted Domain #2
Region A:
Residues: [145-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRRRGRQTYS RYQTLELEKE FLFNPYLTRK RRIEVSHALG LTERQVKIWF QNRRMKWKKE  60
   61 NNKDKFPSSK CEQEELEKEK LERAPETAEQ GDAQKGDKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.0
Match: 1homA
Description: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle