YRC Public Data Repository - Protein Structure Prediction

Protein:	ZFAN5_MOUSE
Organism:	Mus musculus
Length:	213 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ZFAN5_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|61877055 - gi\|61877055\|ref\|XP_585822.1\| PREDICTED: similar to Zinc finger A20 domain containing protein 2 (Zinc...	266.0	[0..1]	[213..22]
gi\|119582938 - gi\|119582938\|gb\|EAW62534.1\| zinc finger, A20 domain containing 2, isoform CRA_b [Homo sapiens] gi\|114624993 - gi\|114624993\|ref\|XP_520073.2\| PREDICTED: similar to zinc finger protein 216 splice variant 1 isoform...	265.0	[0..1]	[213..53]
ZFAND5 - zinc finger, AN1-type domain 5 gi\|109111764, gi... - gi\|109111770\|ref\|XP_001096545.1\| PREDICTED: zinc finger, A20 domain containing 2 isoform 5 [Macaca m... gi\|208968187, gi... - gi\|208968187\|dbj\|BAG73932.1\| zinc finger, AN1-type domain containing protein 5 [synthetic construct]... tr\|M3X338\|M3X338... - Zinc finger AN1-type containing 5 OS=Felis catus GN=ZFAND5 PE=4 SV=1 gi\|73946549, gi\|... - gi\|73946549\|ref\|XP_849428.1\| PREDICTED: similar to Zinc finger A20 domain containing protein 2 (Zinc... gi\|114624999, gi... - gi\|114625001\|ref\|XP_001142059.1\| PREDICTED: zinc finger protein 216 isoform 4 [Pan troglodytes], gi\|...	260.0	[0..1]	[213..1]
ZFAN5_RAT - AN1-type zinc finger protein 5 OS=Rattus norvegicus GN=Zfand5 PE=1 SV=1	256.0	[0..1]	[213..1]
gi\|73946551 - gi\|73946551\|ref\|XP_858773.1\| PREDICTED: similar to Zinc finger A20 domain containing protein 2 (Zinc...	249.0	[0..1]	[213..1]
gi\|147900434, gi... - gi\|51703621\|gb\|AAH81266.1\| MGC86388 protein [Xenopus laevis], gi\|147900434\|ref\|NP_001087815.1\| MGC86...	243.0	[0..1]	[213..1]
gi\|115529238, gi... - gi\|70779223\|gb\|AAZ08234.1\| zinc finger protein 216 [Taeniopygia guttata], gi\|115529238\|ref\|NP_001070...	242.0	[0..1]	[213..1]
gi\|53133400, gi\|... - gi\|71894809\|ref\|NP_001026595.1\| zinc finger protein 216 [Gallus gallus], gi\|53133400\|emb\|CAG32029.1\|...	241.0	[0..1]	[213..1]
gi\|116284288 - gi\|116284288\|gb\|AAI23971.1\| Zinc finger, AN1-type domain 5 [Xenopus tropicalis]	241.0	[0..1]	[213..1]

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Predicted Domain #1

Region A:
Residues: [1-125]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQETNQTPG PMLCSTGCGF YGNPRTNGMC SVCYKEHLQR QQNSGRMSPM GTASGSNSPT  60
   61 SDSASVQRAD AGLNNCEGAA GSTSEKSRNV PVAALPVTQQ MTEMSISRED KITTPKTEVS 120
  121 EPVVT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.39794
Match:	2fidB
Description:	Crystal Structure of a Bovine Rabex-5 fragment complexed with ubiquitin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.06273491536992	bayes_pls_golite062009
protein binding	1.13898499324538	bayes_pls_golite062009
receptor activity	0.805123044711679	bayes_pls_golite062009
transcription regulator activity	0.706335002711624	bayes_pls_golite062009
DNA binding	0.506595018562049	bayes_pls_golite062009
nucleic acid binding	0.356750836914768	bayes_pls_golite062009
signal transducer activity	0.152938475653305	bayes_pls_golite062009
molecular transducer activity	0.152938475653305	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [126-213]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPSPSVSQPS SSQSEEKAPE LPKPKKNRCF MCRKKVGLTG FDCRCGNLFC GLHRYSDKHN  60
   61 CPYDYKAEAA AKIRKENPVV VAEKIQRI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.0
Match:	1wflA
Description:	Solution structure of the zf-AN1 domain from mouse zinc finger protein 216
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: