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View Structure Prediction Details

Protein: C209A_MOUSE
Organism: Mus musculus
Length: 238 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for C209A_MOUSE.

Description E-value Query
Range
Subject
Range
gi|16660119, gi|... - gi|16660119|gb|AAL27539.1|AF374470_1 DC-SIGN neck-less isoform [Mus musculus], gi|148690009|gb|EDL21...
188.0 [0..1] [238..1]
gi|109496327, gi... - gi|34870126|ref|XP_221778.2| PREDICTED: similar to CD209a antigen [Rattus norvegicus], gi|157786866|...
184.0 [0..1] [238..1]
gi|15281085 - gi|15281085|gb|AAK91852.1| sDC-SIGN1A type III isoform [Homo sapiens]
182.0 [0..1] [235..1]
CD209_HYLLA - CD209 antigen OS=Hylobates lar GN=CD209 PE=3 SV=1
175.0 [0..6] [235..186]
209L2_MACMU - CD209 antigen-like protein 2 OS=Macaca mulatta GN=CD209L2 PE=1 SV=1
175.0 [0..1] [235..1]
gi|27356928 - gi|27356928|gb|AAL89544.1| putative CD209 protein [Pan troglodytes]
175.0 [0..6] [235..163]

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Predicted Domain #1
Region A:
Residues: [1-91]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSKEMGKR QLRPLDEELL TSSHTRHSIK GFGFQTNSGF SSFTGCLVHS QVPLALQVLF  60
   61 LAVCSVLLVV ILVKVYKIPS SQEENNQMNV Y

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [92-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QELTQLKAGV DRLCRSCPWD WTHFQGSCYF FSVAQKSWND SATACHNVGA QLVVIKSDEE  60
   61 QNFLQQTSKK RGYTWMGLID MSKESTWYWV DGSPLTLSFM KYWSKGEPNN LGEEDCAEFR 120
  121 DDGWNDTKCT NKKFWICKKL STSCPSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.522879
Match: 1sl6A
Description: Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 1.36045055857751 bayes_pls_golite062009
transmembrane receptor activity 1.10703123577063 bayes_pls_golite062009
signal transducer activity 0.715762096994006 bayes_pls_golite062009
molecular transducer activity 0.715762096994006 bayes_pls_golite062009
binding 0.656008673432897 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle