YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|110804232, gi...
Organism:	Shigella flexneri 5 str. 8401
Length:	182 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|110804232, gi....

Description	E-value	Query Range	Subject Range
lcl\|NC_016856.1_... - [gene=fabZ] [protein=(3R)-hydroxymyristoyl-ACP dehydratase] [protein_id=YP_005235899.1] [location=26... gi\|62126430, gi\|... - gi\|62178797\|ref\|YP_215214.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. enter...	237.0	[0..7]	[182..6]
gi\|68304070\|gb\|A... - FabZ [Escherichia coli] gi\|68304070 - gi\|68304070\|gb\|AAY89693.1\| FabZ [Escherichia coli]	222.0	[0..17]	[182..1]
gi\|421266, gi\|397538 - pir\|\|S35968 (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase (EC 4.2.1.-) - Yersinia enteroc...	208.0	[0..23]	[182..15]
gi\|238784891, gi... - gi\|77957700\|ref\|ZP_00821749.1\| COG0764: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) ... gi\|77963164 - gi\|77963164\|ref\|ZP_00826976.1\| COG0764: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) ...	205.0	[0..23]	[182..15]
gi\|238792744, gi... - gi\|77977737\|ref\|ZP_00833178.1\| COG0764: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) ...	204.0	[0..23]	[182..15]
FABZ_SALPC - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella paratyphi C (strain RKS4594) GN=... gi\|238911293 - gi\|238911293\|ref\|ZP_04655130.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. en... gi\|213648455 - gi\|213648455\|ref\|ZP_03378508.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. en... gi\|213857934 - gi\|213857934\|ref\|ZP_03384905.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. en... gi\|213977105 - gi\|213977105\|ref\|ZP_03404364.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. en... gi\|214000831 - gi\|214000831\|ref\|ZP_03411566.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. en... gi\|213163128 - gi\|213163128\|ref\|ZP_03348838.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. en... gi\|213425953 - gi\|213425953\|ref\|ZP_03358703.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. en... gi\|213580732 - gi\|213580732\|ref\|ZP_03362558.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. en... gi\|213609717 - gi\|213609717\|ref\|ZP_03369543.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. en... FABZ_SALTI - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Salmonella typhi GN=fabZ PE=3 SV=1 FABZ_SALTI - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella typhi GN=fabZ PE=3 SV=1 FABZ_SALCH - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Salmonella choleraesuis GN=fabZ PE=3 SV=... gi\|16759217 - gi\|16759217\|ref\|NP_454834.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. enter... FABZ_SALPA - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella paratyphi A (strain ATCC 9150 / ... FABZ_SALTY - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Salmonella typhimurium GN=fabZ PE=3 SV=1 FABZ_SALTY - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella typhimurium (strain LT2 / SGSC14... FABZ_SALPB - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella paratyphi B (strain ATCC BAA-125... gi\|29136391, gi\|... - gi\|29140767\|ref\|NP_804109.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Salmonella enterica subsp. enter... FABZ_SALPA - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Salmonella paratyphi A GN=fabZ PE=3 SV=1 FABZ_SALAR - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella arizonae (strain ATCC BAA-731 / ... FABZ_SALTY - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Salmonella typhimurium GN=fabZ PE=3 SV=1 FABZ_SALCH - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Salmonella choleraesuis GN=fabZ PE=3 SV=... gi\|167553359, gi... - gi\|205322195\|gb\|EDZ10034.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella ent... gi\|205331320, gi... - gi\|205331320\|gb\|EDZ18084.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella ent... gi\|168230536, gi... - gi\|205335094\|gb\|EDZ21858.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella ent... gi\|197291849, gi... - gi\|197291849\|gb\|EDY31199.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella ent... FABZ_SALPB - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Salmonella paratyphi B (strain ATCC BAA-... gi\|200388350, gi... - gi\|200388350\|ref\|ZP_03214962.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella... gi\|204927047, gi... - gi\|204927047\|ref\|ZP_03218249.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella... FABZ_SALG2 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella gallinarum (strain 287/91 / NCTC... FABZ_SALCH - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella choleraesuis (strain SC-B67) GN=... FABZ_SALEP - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella enteritidis PT4 (strain P125109)... FABZ_SALA4 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella agona (strain SL483) GN=fabZ PE=... gi\|197262248, gi... - gi\|197262248\|ref\|ZP_03162322.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella... FABZ_SALPK - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella paratyphi A (strain AKU_12601) G... FABZ_SALDC - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella dublin (strain CT_02021853) GN=f... FABZ_SALNS - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella newport (strain SL254) GN=fabZ P... FABZ_SALHS - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella heidelberg (strain SL476) GN=fab... gi\|194456267, gi... - gi\|194469903\|ref\|ZP_03075887.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella... FABZ_SALSV - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Salmonella schwarzengrund (strain CVM19633)... gi\|205336206, gi... - gi\|205336206\|gb\|EDZ22970.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella ent... gi\|168264635, gi... - gi\|205346923\|gb\|EDZ33554.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella ent... gi\|195632581, gi... - gi\|195632581\|gb\|EDX51035.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella ent... gi\|205340612, gi... - gi\|205340612\|gb\|EDZ27376.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Salmonella ent...	201.0	[0..32]	[182..1]
FABZ_YERPY - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pseudotuberculosis serotype O:3 (s... gi\|167470462 - gi\|167470462\|ref\|ZP_02335166.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p... FABZ_YERPB - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pseudotuberculosis serotype IB (st... FABZ_YERPS - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pseudotuberculosis serotype I (str... FABZ_YERP3 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pseudotuberculosis serotype O:1b (... FABZ_YERPG - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pestis bv. Antiqua (strain Angola)... gi\|166207125, gi... - gi\|166211354\|ref\|ZP_02237389.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p... gi\|166011911, gi... - gi\|166011911\|ref\|ZP_02232809.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p... gi\|229704139, gi... - gi\|229837762\|ref\|ZP_04457922.1\| (3R)-hydroxymyristol acyl carrier protein dehydratase [Yersinia pest... gi\|167055736, gi... - gi\|167425336\|ref\|ZP_02317089.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p... gi\|167399930, gi... - gi\|167399930\|ref\|ZP_02305448.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p... FABZ_YERPA - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pestis bv. Antiqua (strain Antiqua... FABZ_YERPP - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pestis (strain Pestoides F) GN=fab... FABZ_YERPN - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pestis bv. Antiqua (strain Nepal51... gi\|45437428, gi\|... - gi\|45442563\|ref\|NP_994102.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Yersinia pestis biovar Microtus ... gi\|21960046, gi\|... - gi\|22127000\|ref\|NP_670423.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Yersinia pestis KIM], gi\|2196004... FABZ_YERPS - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Yersinia pseudotuberculosis GN=fabZ PE=3...	201.0	[0..32]	[182..1]
FABZ_YERPE - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Yersinia pestis GN=fabZ PE=3 SV=1 gi\|165939810, gi... - gi\|89105145\|ref\|ZP_01177670.1\| COG0764: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) ... gi\|15979122, gi\|... - gi\|218928223\|ref\|YP_002346098.1\| (3R)-hydroxymyristoyl-ACP dehydratase [Yersinia pestis CO92], gi\|16... gi\|165927057, gi... - gi\|165927057\|ref\|ZP_02222889.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p... gi\|149290558, gi... - gi\|149366944\|ref\|ZP_01888977.1\| (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase [Yersinia p... gi\|229840984, gi... - gi\|229840984\|ref\|ZP_04461143.1\| (3R)-hydroxymyristol acyl carrier protein dehydratase [Yersinia pest... gi\|229689961, gi... - gi\|229843085\|ref\|ZP_04463235.1\| (3R)-hydroxymyristol acyl carrier protein dehydratase [Yersinia pest... gi\|166962486, gi... - gi\|167419745\|ref\|ZP_02311498.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Yersinia p...	201.0	[0..32]	[182..1]
FABZ_PECAS - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Pectobacterium atrosepticum (strain SCRI 10... FABZ_ERWCT - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Erwinia carotovora subsp. atroseptica GN...	201.0	[0..32]	[182..1]

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Predicted Domain #1

Region A:
Residues: [1-182]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFAKLYGLSH SYDCGRPCYY CRFLYFDRKS ILTTNTHTLQ IEEILELLPH RFPFLLVDRV  60
   61 LDFEEGRFLR AVKNVSVNEP FFQGHFPGKP IFPGVLILEA MAQATGILAF KSVGKLEPGE 120
  121 LYYFAGIDEA RFKRPVVPGD QMIMEVTFEK TRRGLTRFKG VALVDGKVVC EATMMCARSR 180
  181 EA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.39794
Match:	1u1zA
Description:	The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
CoA hydrolase activity	1.75530090056705	bayes_pls_golite062009
catalytic activity	1.11649534052993	bayes_pls_golite062009
thiolester hydrolase activity	0.65794221902015	bayes_pls_golite062009
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	0.57527342054578	bayes_pls_golite062009
3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	0.57527342054578	bayes_pls_golite062009
acyl-CoA thioesterase activity	0.24094527143225	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: