YRC Public Data Repository - Protein Structure Prediction

Protein:	NEP1_MOUSE
Organism:	Mus musculus
Length:	244 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NEP1_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|164607178, gi... - gi\|27713326\|ref\|XP_232345.1\| PREDICTED: similar to Probable ribosome biogenesis protein NEP1 (C2f pr...	429.0	[0..1]	[244..1]
gi\|114643126 - gi\|114643126\|ref\|XP_508978.2\| PREDICTED: C2f protein [Pan troglodytes]	418.0	[0..1]	[244..1]
EMG1 - EMG1 nucleolar protein homolog (S. cerevisiae)	418.0	[0..1]	[244..1]
gi\|73997287 - gi\|73997287\|ref\|XP_853373.1\| PREDICTED: similar to Probable ribosome biogenesis protein NEP1 (C2f pr...	410.0	[0..1]	[244..1]
gi\|109095424 - gi\|109095424\|ref\|XP_001118315.1\| PREDICTED: EMG1 nucleolar protein homolog (S. cerevisiae) [Macaca m...	407.0	[0..1]	[244..1]
gi\|55241966, gi\|... - gi\|58382693\|ref\|XP_312105.2\| AGAP002808-PA [Anopheles gambiae str. PEST], gi\|55241966\|gb\|EAA07709.3\|... AGAP002808-PA - rRNA small subunit pseudouridine methyltransferase Nep1\|protein_coding\|2R:27877043:27877912:-1\|gene:...	342.0	[0..11]	[244..3]
gi\|108882524, gi... - gi\|157126756\|ref\|XP_001654738.1\| nucleolar essential protein 1 (nep1) [Aedes aegypti], gi\|108882524\|...	340.0	[0..11]	[244..3]
CG3527-PA - This gene is referred to in FlyBase by the symbol Dmel\CG3527 (CG3527, FBgn0029714). It is a protein...	340.0	[0..13]	[244..17]

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Predicted Domain #1

Region A:
Residues: [1-244]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAASGGFQP RERRFSVQEQ DWETTPPKKL RLGAGSKCGG RRLIVVLEGA SLETVKVGKT  60
   61 YELLNCDRHK SMLLKNGRDP GEVRPDITHQ SLLMLMDSPL NRAGLLQVYI HTQKNVLIEV 120
  121 NPQTRIPRTF DRFCGLMVQL LHKLSVRAAD GPQKLLKVIK NPVSDHFPVG CMKIGTSFSV 180
  181 EDISDIRELV PSSDPVVFVV GAFAHGKVSV EYTEKMVSIS NYPLSAALTC AKVTTAFEEV 240
  241 WGVI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	85.69897
Match:	2v3kA
Description:	No description for 2v3kA was found.

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	3.73300070859272	bayes_pls_golite062009
tRNA methyltransferase activity	2.75506106783732	bayes_pls_golite062009
methyltransferase activity	2.52574509568717	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	2.44351066049012	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.00166711852993	bayes_pls_golite062009
RNA binding	1.99948490385053	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	1.9680534181971	bayes_pls_golite062009
rRNA methyltransferase activity	1.94772102267592	bayes_pls_golite062009
binding	1.07947949398964	bayes_pls_golite062009
nucleic acid binding	0.987186921436979	bayes_pls_golite062009
catalytic activity	0.797300463760338	bayes_pls_golite062009
transferase activity	0.489526737652591	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.425953878527171	bayes_pls_golite062009
protein binding	0.303628351374506	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: