YRC Public Data Repository - Protein Structure Prediction

Protein:	YHMA_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	581 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YHMA_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|70984531, gi\|... - gi\|70984531\|ref\|XP_747772.1\| MFS multidrug transporter [Aspergillus fumigatus Af293], gi\|66845399\|gb... gi\|159122556 - gi\|159122556\|gb\|EDP47677.1\| MFS multidrug transporter, putative [Aspergillus fumigatus A1163]	190.0	[0..5]	[552..113]
gi\|46107656, gi\|... - gi\|46107656\|ref\|XP_380887.1\| hypothetical protein FG00711.1 [Gibberella zeae PH-1], gi\|42547814\|gb\|E...	188.0	[0..3]	[514..1379]
SNF3 - Plasma membrane low glucose sensor that regulates glucose transport; contains 12 predicted transmemb... SNF3_YEAST - High-affinity glucose transporter SNF3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=S...	183.0	[0..3]	[557..43]
gi\|115928814, gi... - gi\|72179189\|ref\|XP_798448.1\| PREDICTED: similar to solute carrier family 2 (facilitated glucose tran...	180.0	[0..11]	[559..23]
gi\|49072098, gi\|... - gi\|71016129\|ref\|XP_758870.1\| hypothetical protein UM02723.1 [Ustilago maydis 521], ref\|XP_400338.1\| ...	180.0	[0..4]	[566..121]
gi\|67522038, gi\|... - gi\|67522038\|ref\|XP_659080.1\| hypothetical protein AN1476.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	178.0	[0..8]	[559..424]
gi\|60467752, gi\|... - gi\|60467752\|gb\|EAL65769.1\| hypothetical protein DDB0191430 [Dictyostelium discoideum], gi\|29500764\|g... gi\|60467752, gi\|... - gi\|66810832\|ref\|XP_639123.1\| major facilitator superfamily transporter [Dictyostelium discoideum AX4...	177.0	[0..52]	[513..595]
gi\|39944294, gi\|... - gi\|39944294\|ref\|XP_361684.1\| hypothetical protein MGG_04158 [Magnaporthe grisea 70-15], gb\|EAA50399....	176.0	[0..16]	[567..94]

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Predicted Domain #1

Region A:
Residues: [1-516]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPDGYVEEL PGTILIYKEN QYAASEHSVL KKDGDIVLQP QPSDDPNDPL NWNKFRKNWH  60
   61 LVLICLVSLV TGAIANDAGS AQDQMNAELG ISYDAMDNAA GVLFICVGYF TYLAMPATFL 120
  121 YGRRCVYLVC LLFGMLGSMW FALVKTTSNS IGNQAFIGIS EACAEALTQF SVSEVFFEHE 180
  181 RGIKIGIYIL STSVGTYLGP LAAGYIASSQ GWRWIGWWGL IISGITFVLF LFTFEETTFD 240
  241 RAAAIDRKQI QISNDQLTVK EDFDLKDMQS DIKPDVEKSD AMDDSKMKVD YTVNEISNAV 300
  301 QPIYSKPSYW KRIALITPAN SLSGIGFRQY IMRLFQTLRI FLFPAVLYSG LQWGAQDAWL 360
  361 SFYLTTEEED WMEAPYNYGD NAVAIMNVPC IIGATIGCIY GGYFGDYFTL WAAKRNNGIK 420
  421 EAESRLWLMI LPCIINPIGL FMFGIGTARH WHWGPTYVGL GFIGFGWGCA GDISMAYLMD 480
  481 AYPGMVLEAM VGVSVINNTF GYVFTFACQS WIDSLG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.0
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
substrate-specific transmembrane transporter activity	5.21742729128468	bayes_pls_golite062009
ion transmembrane transporter activity	4.31748220369305	bayes_pls_golite062009
transporter activity	4.09176719149278	bayes_pls_golite062009
cation transmembrane transporter activity	4.0441553876112	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transporter activity	3.3426261924492	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
anion transmembrane transporter activity	1.03584454754608	bayes_pls_golite062009
binding	1.01584233411372	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [517-581]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TERTYISIGV LCFIFIATSF PMILCGKRLR KWTAKQYYTF LNVRNRLDEK IPDQDRRGQD  60
   61 GVESR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: