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View Structure Prediction Details

Protein: DCP2_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 741 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DCP2_SCHPO.

Description E-value Query
Range
Subject
Range
gi|74212506, gi|... - gi|74212506|dbj|BAE30995.1| unnamed protein product [Mus musculus], gi|74142254|dbj|BAE31891.1| unna...
436.0 [0..2] [378..3]
gi|109078230 - gi|109078230|ref|XP_001082528.1| PREDICTED: similar to DCP2 decapping enzyme isoform 2 [Macaca mulat...
431.0 [0..2] [338..3]
gi|114672434 - gi|114672434|ref|XP_001147135.1| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]
429.0 [0..2] [338..3]
DCP2 - DCP2 decapping enzyme homolog (S. cerevisiae)
427.0 [0..2] [338..3]
gi|109506558, gi... - gi|109514053|ref|XP_001055777.1| PREDICTED: similar to mRNA decapping enzyme 2 [Rattus norvegicus], ...
426.0 [0..2] [377..76]

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Predicted Domain #1
Region A:
Residues: [1-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFTNATFSQ VLDDLSARFI LNLPAEEQSS VERLCFQIEQ AHWFYEDFIR AQNDQLPSLG  60
   61 LRVFSAKLFA HCPLLWKWSK VHEEAFDDFL RYKTRIPVRG AIMLDMSMQQ CVLVKGWKAS 120
  121 SGWGFPKGKI DKDESDVDCA IREVYEETGF DCSSRINPNE FIDMTIRGQN VRLYIIPGIS 180
  181 LDTRFESRTR KEISKIEWHN LMDLPTFKKN KPQTMKNKFY MVIPFLAPLK KWIKKRNIAN 240
  241 N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 104.0
Match: 2a6tA
Description: Crystal structure of S.pombe mRNA decapping enzyme Dcp2p
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [242-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTKEKNISVD VDADASSQLL SLLKSSTAPS DLATPQPSTF PQPPVESHSS FDIKQKILHL  60
   61 LNEGNEPKSP IQLPPVSNLP LNPPIQSSNS RLSH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [336-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNNSFDPFAY LGLDPKNPSA SFPRVVSQNN MLTNKPVLNN HFQQSMYSNL LKDQNSVQHL  60
   61 FAASDMPSPM ELPSPSTVYH QVFYPPTSTS VSSYGLGKTP QPAYGSSSPY VNGHQTQQIS 120
  121 SLPPFQSQTQ FLARNSDNSG Q

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [477-617]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYNSEGDSNS KRLLSMLSQQ DTTPSSSTLS KEANVQLANL FLTPNSLETK KFSDNSQGEE  60
   61 ISDNLHGESC NNPNANSVHS AQLLQALLHP SATETKEETP KKTSDSLSLL TLLKSGLPTP 120
  121 ANDLQNKSQN NERKASSQVK E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.561 0.858 mRNA processing a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #5
Region A:
Residues: [618-741]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEVKNYSKST DLLKKTLRIP RNDEPLEAAN QFDLLKVSPQ QKSEVPPKRN ELSQSKLKNR  60
   61 KKKENSETNK NHVDMSPGFV KILKRSPLAD QKKEDTQESD FKGSDDHFLS YLQSVVSSNS 120
  121 NGLH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle