YRC Public Data Repository - Protein Structure Prediction

Protein:	PEX13_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	288 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEX13_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|207342984 - gi\|207342984\|gb\|EDZ70588.1\| YLR191Wp-like protein [Saccharomyces cerevisiae AWRI1631] PEX13_YEAST - Peroxisomal membrane protein PAS20 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEX13... PEX13 - Integral peroxisomal membrane required for the translocation of peroxisomal matrix proteins, interac...	223.0	[0..6]	[288..66]
gi\|119195595, gi... - gi\|90307187\|gb\|EAS36818.1\| hypothetical protein CIMG_02172 [Coccidioides immitis RS], gi\|119195595\|r...	213.0	[0..67]	[288..24]
gi\|26327789 - gi\|26327789\|dbj\|BAC27635.1\| unnamed protein product [Mus musculus]	212.0	[0..9]	[288..54]
gi\|114577535 - gi\|114577535\|ref\|XP_525763.2\| PREDICTED: peroxisome biogenesis factor 13 [Pan troglodytes] PEX13 - peroxisomal biogenesis factor 13	211.0	[0..9]	[288..52]
gi\|6682845 - gi\|6682845\|dbj\|BAA88906.1\| PEX13 [Cricetulus griseus]	210.0	[0..9]	[288..54]
gi\|109501111, gi... - ref\|XP_223684.2\| similar to Peroxisomal membrane protein PEX13 (Peroxin-13) [Rattus norvegicus], gi\|...	210.0	[0..9]	[288..52]
gi\|49087424, gi\|... - gi\|67522108\|ref\|XP_659115.1\| hypothetical protein AN1511.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	209.0	[0..64]	[288..135]
gi\|42545553, gi\|... - gi\|46107566\|ref\|XP_380842.1\| hypothetical protein FG00666.1 [Gibberella zeae PH-1], gi\|42545553\|gb\|E...	209.0	[0..67]	[288..213]

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Predicted Domain #1

Region A:
Residues: [1-102]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METNQNEKGP SLPSYPAGGI MSVSNSNADT NQGVTQHPLA NRIVNPNYYN MGFNPYSGFN  60
   61 SFIPSFNPFV PLETNLPGNG PISSLQVIES IVGAVGSIAQ VL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [103-193]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESTLMAAHMS YNTFVSVSEN LNKLKSSIGA IFGIVSLLSR LKRLVLKFFK HSKIDEMNSQ  60
   61 EYDVFEKEEG NHKNSIYSIV SSLAIILGLV G

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.0
Match:	1zwwA
Description:	Crystal structure of endophilin-A1 BAR domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [194-288]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPYAIIRLFK NIYEKEKQIQ QAKIRKKIDS LEFCKADYEF MSRDPGVEMS LKKGDIIAIL  60
   61 SKTDTQGNPC EWWQGRKRSG ETGWFPSNYC SIISR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.0
Match:	1jqqA
Description:	Peroxisomal membrane protein Pex13p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.49184519104882	bayes_pls_golite062009
protein binding	2.29371158534719	bayes_pls_golite062009
cytoskeletal protein binding	1.67112127425228	bayes_pls_golite062009
transporter activity	1.30447542854757	bayes_pls_golite062009
transmembrane transporter activity	1.08558010881058	bayes_pls_golite062009
actin binding	0.75525840382431	bayes_pls_golite062009
substrate-specific transporter activity	0.566172161499832	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.325817349097199	bayes_pls_golite062009
ion transmembrane transporter activity	0.00508584255499911	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: