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View Structure Prediction Details

Protein: RIO1_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 521 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RIO1_SCHPO.

Description E-value Query
Range
Subject
Range
KPCL_MOUSE - Protein kinase C eta type OS=Mus musculus GN=Prkch PE=2 SV=1
245.0 [0..82] [476..300]
KPCL_RAT - Protein kinase C eta type OS=Rattus norvegicus GN=Prkch PE=1 SV=1
244.0 [0..82] [476..300]
gi|47213332 - gi|47213332|emb|CAF93963.1| unnamed protein product [Tetraodon nigroviridis]
244.0 [0..31] [480..383]
gi|73963103 - gi|73963103|ref|XP_547844.2| PREDICTED: similar to protein kinase C, eta isoform 1 [Canis familiaris...
242.0 [0..101] [470..312]
gi|110761240 - gi|110761240|ref|XP_396874.3| PREDICTED: similar to Akt1 CG4006-PA, isoform A [Apis mellifera]
241.0 [0..142] [478..182]
gi|458284 - gi|458284|gb|AAA57318.1| serine/threonine protein kinase
241.0 [0..53] [479..229]
gi|118782294, gi... - gi|118782294|ref|XP_312175.3| ENSANGP00000022036 [Anopheles gambiae str. PEST], gi|116129500|gb|EAA0...
241.0 [0..57] [456..313]

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Predicted Domain #1
Region A:
Residues: [1-115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEELKNDAQ TNEEESEYSD FSDGSDNDYF REDDIDWNQA SSNYSARQEN FGNNSSKINS  60
   61 VNDHVSTLSR YVNNIKLNDR FEAEGFRTRG LLILHTFTFS CLIVLTNKDK SSIKD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [116-521]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSDRATSEQV LDPRTRMILL KLINNGTISE INGCISTGKE ANVYHATNED GKHFAIKIYK  60
   61 TSILVFKDRD RYVSGEFRFR HGYNKRNPRK MVRLWAEKEI RNLKRVAAAG IPCPEPILLK 120
  121 QHVLLMSFLG DKKGWAYPKL KDIDMTPGEA TKLYQLVARN MRILFHVCHL VHADLSEYNL 180
  181 LYHKGKVYFI DVSQSVEHDH PQSIDFLRMD ILNISTFFRR LNAGCLSLPQ LFKFITEEGS 240
  241 CEKEAMKTRL NAIYEEEPTT EEYEEEFLKT YVPRTLDEVY DIDRDTEIVN AGGVNSLVYK 300
  301 HLLNTDFQKL DLNDTTKNQN DQILPNETSE SDDDANSISS MENEEERTSD SKSSAKQGKG 360
  361 NGRAKETPEE KRARKKKTKE DKAEKRKSKI PKYEKKRKLK QSGRKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.0
Match: 1m7qA
Description: MAP kinase p38
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.74863538127007 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.68629765438914 bayes_pls_golite062009
protein kinase activity 2.56362090019902 bayes_pls_golite062009
kinase activity 2.46700969159892 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.17888523666192 bayes_pls_golite062009
protein serine/threonine kinase activity 1.66424140461588 bayes_pls_golite062009
transferase activity 1.58037420753723 bayes_pls_golite062009
protein binding 1.22565748038754 bayes_pls_golite062009
ATP binding 0.261039303134118 bayes_pls_golite062009
adenyl ribonucleotide binding 0.215871730509016 bayes_pls_golite062009
adenyl nucleotide binding 0.199843476277027 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.016674711694129 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle