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View Structure Prediction Details

Protein: YKIC_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 422 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKIC_SCHPO.

Description E-value Query
Range
Subject
Range
gi|20070434, gi|... - ref|NP_075563.2| metallophosphoesterase 1 [Homo sapiens], gi|19880267|gb|AAM00279.1|AF363484_1 meta...
247.0 [0..2] [375..19]
gi|55647249 - gi|55647249|ref|XP_523860.1| PREDICTED: metallophosphoesterase 1 isoform 14 [Pan troglodytes]
247.0 [0..2] [375..19]
MPPE1_MACFA - Metallophosphoesterase 1 OS=Macaca fascicularis GN=MPPE1 PE=2 SV=1
245.0 [0..2] [377..19]
gi|109121523, gi... - gi|109121529|ref|XP_001095654.1| PREDICTED: similar to metallophosphoesterase 1 precursor isoform 6 ...
244.0 [0..2] [377..19]
MPPE1_MOUSE - Metallophosphoesterase 1 OS=Mus musculus GN=Mppe1 PE=2 SV=1
242.0 [0..9] [382..28]

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Predicted Domain #1
Region A:
Residues: [1-422]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVGRFLVII AFCFYVLYLE KIIHTRPHKK CDWRSWEQWE STGNPVRIAL VADPQLVDDL  60
   61 TYDYPRPLIG IVKWISDQFL RRHWRYLHKS LKPDITFIMG DLMDTGREFA TEEFKKDYFR 120
  121 MMNVLDPKFT NKLEIYPGNH DIGFGNHAIV KDIQRFESLF GPTSRSIDVG NHTLVIVDGI 180
  181 RLSNNVNPQV YQPARDFLKS FETNKDNSRP RILLSHVPLF RPAINSCGEL REKDDVIKYG 240
  241 LGYQYQNLLL PELSESILKA VEPIAAFAGD DHDYCEVVHN YQVDTREAAT TEYNVKAFSM 300
  301 TSGILYPGYQ LLSLNYPYDN PKADQKSSYQ TKLCILPNQI QIYVWYGASI SIFFALILLR 360
  361 TAIFFFGTDR YSLPLYKTHA RRFSLSTTIH LFKKIVRITL STFISYTWIP FLLFIFLNIF 420
  421 II

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.221849
Match: 1kbpA
Description: Purple acid phosphatase, N-terminal domain; Plant purple acid phosphatase, catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
signal transducer activity 1.5323377955218 bayes_pls_golite062009
molecular transducer activity 1.5323377955218 bayes_pls_golite062009
phosphoric ester hydrolase activity 1.23907194592674 bayes_pls_golite062009
binding 1.01605260539008 bayes_pls_golite062009
phosphoprotein phosphatase activity 1.0113813500732 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.855953242290295 bayes_pls_golite062009
phosphatase activity 0.709873667529051 bayes_pls_golite062009
protein serine/threonine phosphatase activity 0.547141398411243 bayes_pls_golite062009
hydrolase activity 0.439219554159025 bayes_pls_golite062009
protein binding 0.283905381578004 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle