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View Structure Prediction Details

Protein: NMAH_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 365 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NMAH_SCHPO.

Description E-value Query
Range
Subject
Range
gi|45201117, gi|... - gi|45201117|ref|NP_986687.1| AGR022Cp [Ashbya gossypii ATCC 10895], gi|44985900|gb|AAS54511.1| AGR02...
gi|44985900 - gi|44985900|gb|AAS54511.1| AGR022Cp [Ashbya gossypii ATCC 10895]
319.0 [0..6] [359..61]
gi|68474566, gi|... - gi|68474566|ref|XP_718656.1| hypothetical protein CaO19.7499 [Candida albicans SC5314], gi|46440435|...
orf19.7499 - orf19.7499 CGDID:CAL0005752 Assembly 19, Contig19-2516 (79362, 78157) CDS, reverse complemented, tra...
315.0 [0..7] [358..53]
NMA2 - Nicotinic acid mononucleotide adenylyltransferase, involved in de novo and salvage synthesis of NAD(...
NMA2_YEAST - Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 OS=Saccharomyces cerevisiae (strain...
313.0 [0..15] [358..60]
gi|46102040, gi|... - gi|71024819|ref|XP_762639.1| hypothetical protein UM06492.1 [Ustilago maydis 521], ref|XP_404107.1| ...
307.0 [0..3] [358..237]
gi|49524117, gi|... - gi|50284775|ref|XP_444815.1| hypothetical protein CAGL0A01023g [Candida glabrata CBS138], gi|4952411...
gi|49524117 - gi|49524117|emb|CAG57706.1| unnamed protein product [Candida glabrata]
279.0 [0..2] [358..43]
gi|50419319, gi|... - gi|50419319|ref|XP_458184.1| hypothetical protein DEHA0C12639g [Debaryomyces hansenii CBS767], gi|49...
273.0 [0..7] [358..43]
gi|49642138, gi|... - gi|50306087|ref|XP_453005.1| unnamed protein product [Kluyveromyces lactis], gi|49642138|emb|CAH0185...
gi|49642138 - gi|49642138|emb|CAH01856.1| KLLA0C18051p [Kluyveromyces lactis]
259.0 [0..75] [359..163]
gi|49650260, gi|... - gi|50553965|ref|XP_504391.1| YALI0E25652p [Yarrowia lipolytica], gi|49650260|emb|CAG79991.1| YALI0E2...
gi|49650260 - gi|49650260|emb|CAG79991.1| YALI0E25652p [Yarrowia lipolytica]
253.0 [0..33] [358..148]
gi|67522577, gi|... - gi|67522577|ref|XP_659349.1| hypothetical protein AN1745.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
251.0 [0..100] [365..20]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGDNFANSF PKNPLLSRNS SSSNVIQYSD EFSPDEDWLN EHAAKEHEER IRRPSVNRAW  60
   61 QKNSTSGGPS VSLEKREADV ASLGEVMDLE EVPRGITRQA RQLNEYIFPK HRFRNH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [117-365]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVDEGKIPLV LVACGSFSPI TYLHLRMFEM ATDTIQEQTN MELVAGYFSP VNDHYKKEGL  60
   61 APAYHRVRMC ELACERTSSW LMVDAWESLQ PSYTCTARVL DHFDEEINQK RGGITLSDGT 120
  121 KRPCKIMLLA GGDLIASMGE PGVWSDKDLH HILGKFGCCI VERTGSDVWA FLLAHDIMFA 180
  181 YRGNILVIKQ LIYNDISSTK VRLFIRRGMS IRYLLPNSVI QYIERYALYR DAEPVKTIFY 240
  241 QSPFVRMEP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.69897
Match: 1kqnA
Description: Nicotinamide mononucleotide (NMN) adenylyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nicotinate-nucleotide adenylyltransferase activity 2.94996967804011 bayes_pls_golite062009
nicotinamide-nucleotide adenylyltransferase activity 2.8149071156304 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 2.54008423253828 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 2.54008423253828 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 2.52910114154477 bayes_pls_golite062009
catalytic activity 2.37674226834122 bayes_pls_golite062009
ligase activity 1.92894388839884 bayes_pls_golite062009
binding 1.11291710031577 bayes_pls_golite062009
adenylyltransferase activity 1.08055019963499 bayes_pls_golite062009
nucleic acid binding 0.623161608923414 bayes_pls_golite062009
nucleotidyltransferase activity 0.564359271862248 bayes_pls_golite062009
pantetheine-phosphate adenylyltransferase activity 0.454904507512502 bayes_pls_golite062009
pantoate-beta-alanine ligase activity 0.282286652169846 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle