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View Structure Prediction Details

Protein: YCTB_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 476 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YCTB_SCHPO.

Description E-value Query
Range
Subject
Range
gi|49903949, gi|... - gi|50300479|ref|NP_001002022.1| enthoprotin [Rattus norvegicus], gi|49903949|gb|AAH76397.1| Enthopro...
261.0 [0..11] [466..2]
gi|111307118 - gi|111307118|gb|AAI20215.1| EPN2 protein [Bos taurus]
244.0 [0..14] [252..1]
gi|26006105 - gi|26006105|dbj|BAC41396.1| mKIAA0171 protein [Mus musculus]
236.0 [0..25] [466..35]
gi|119615012, gi... - gi|50417637|gb|AAH77722.1| EPN3 protein [Homo sapiens], gi|30411009|gb|AAH51365.1| EPN3 protein [Hom...
226.0 [0..14] [222..1]
gi|114188015, gi... - gi|115442678|ref|XP_001218146.1| conserved hypothetical protein [Aspergillus terreus NIH2624], gi|11...
219.0 [0..2] [418..4]
gi|3763925, gi|2... - gi|3763925|gb|AAC64305.1| putative clathrin binding protein (epsin) [Arabidopsis thaliana], pir||G84...
209.0 [0..8] [263..1]

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Predicted Domain #1
Region A:
Residues: [1-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESIQSTMKN INLYDIKAAV RKAQNVVMNY TSMEARVREA TNNEPWGAST SLMMEIAQGT  60
   61 HNYSQLNEIL PMIYRRFTEK TAEEWRQIYK ALQLLEFLVK NGSERVVDDA RAHQATIKML 120
  121 RNFHYIDHRQ KDQGLNVRTR AKELVELLND SERIRKERKR ARQNR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.522879
Match: 1h0aA
Description: Epsin 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 7.05477548709703 bayes_pls_golite062009
binding 2.34501465852339 bayes_pls_golite062009
protein binding 1.97365365208963 bayes_pls_golite062009
phospholipid binding 1.38798066582556 bayes_pls_golite062009
phosphoinositide binding 1.26458267960741 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 1.20269437433936 bayes_pls_golite062009
ADP-ribosylation factor binding 0.95608914040147 bayes_pls_golite062009
lipid binding 0.176990783274449 bayes_pls_golite062009
GTPase binding 0.0887270623721197 bayes_pls_golite062009
small GTPase binding 0.0268749201897704 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [166-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKFIGVGSDG DSRISTSSKS RFPSFGSSRG SYRTRVYGDG GGFTDYGNGY HDSSSMSDSR  60
   61 DASDNDVEEY NEDGDGGSSD AATANSTRGS RRTTTKQSDK APEQPKQESA MIDLLGLDNE 120
  121 PSPAQPQTNT SAPLAFEDDG FGDFQSSAAA PASSTLNNAS LFMGSQTAST AAKNDDDAFD 180
  181 D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [347-476]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQSAPSAKPA SNTAAFSSIS FGGFNSLNQL PTSSSAFTPQ PTTFNTGYTS AFGMSSGLSN  60
   61 TSSQAGLGLT SQQPTAAKSS GSNGDAFGSL WSSAVNKVHQ ENSTRERVVS SSSEPVSKTQ 120
  121 NFLDNDNLLL 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle