YRC Public Data Repository - Protein Structure Prediction

Protein:	PGPS1_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	534 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGPS1_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|27364601, gi\|... - gi\|27364601\|ref\|NP_760129.1\| phosphatidylserine synthase [Vibrio vulnificus CMCP6], gi\|27360720\|gb\|A... gi\|37200108, gi\|... - gi\|37681356\|ref\|NP_935965.1\| phosphatidylserine synthase [Vibrio vulnificus YJ016], gi\|37200108\|dbj\|...	307.0	[0..19]	[532..9]
gi\|76098908 - gi\|76098908\|gb\|AAH25951.2\| PGS1 protein [Homo sapiens]	293.0	[0..2]	[533..67]
gi\|114670716 - gi\|114670716\|ref\|XP_001157355.1\| PREDICTED: phosphatidylglycerophosphate synthase 1 isoform 3 [Pan t...	293.0	[0..2]	[533..74]
gi\|109118496 - gi\|109118496\|ref\|XP_001108217.1\| PREDICTED: similar to CG7718-PA [Macaca mulatta]	292.0	[0..2]	[533..74]
gi\|19386924 - gi\|19386924\|gb\|AAL87040.1\|AF411101_1 silencer-associated factor [Mus musculus]	291.0	[0..2]	[533..31]
gi\|73964965 - gi\|73964965\|ref\|XP_533128.2\| PREDICTED: similar to phosphatidylglycerophosphate synthase [Canis fami...	291.0	[0..2]	[533..141]
gi\|55730362 - gi\|55730362\|emb\|CAH91903.1\| hypothetical protein [Pongo abelii] PGPS1_PONAB - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial OS=Pongo abelii GN...	291.0	[0..2]	[533..74]
gi\|115438166, gi... - gi\|115438166\|ref\|XP_001217996.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	290.0	[0..16]	[529..55]
PGPS1_YEAST - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase OS=Saccharomyces cerevisiae (stra... gi\|207347342 - gi\|207347342\|gb\|EDZ73542.1\| YCL004Wp-like protein [Saccharomyces cerevisiae AWRI1631] PGS1 - Phosphatidylglycerolphosphate synthase, catalyzes the synthesis of phosphatidylglycerolphosphate fro...	290.0	[0..14]	[534..47]

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Predicted Domain #1

Region A:
Residues: [1-534]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEGIEKNIF VNLESQIDGV CPKFYVNVDD IDIIHEPPEF YQRLKKLIKK AQKRIFLSTL  60
   61 YIGKEERELI NCLSNALSNN PSLHVHILAD QLRCTRESPG CCSASLLMQL KKKFPDRCEI 120
  121 KLYHTPNLRG LRKQLVPHRF NEGWGLQHMK IYGADDNLII SGANLSRDYF TNRKDRYYLF 180
  181 SDKGLADFFF KTHFLFSQLS FECIPHLSDS SIQLSSTSPV IPFTLKWNNS CPNPLTNPQE 240
  241 FRVAASAKIQ QLLQGNREKF LSRNPSKPLS SVYGSELINQ AGDDNNKPFH KYEESAIVYP 300
  301 LFQCVPILTS DVHSTEEKVL SIIGTLLSRK EVNWTLTAGY FNVYPALRKQ LLKSEGIGEV 360
  361 IVASQQANGF YRSPGPSKLI PPAYQYIAEQ FLKDSRKKKR NIDVLQWQNK GNTYHAKGKH 420
  421 YSLSFSIINI FWSTALKSYI FEKFTNTILG FWLSTQHHKH PFLTTIGSSN YTSRSQQLDL 480
  481 ESTLVVMTQN EKLKRKFSTE IELIKQHTKP MNTCQLEKVP MYVKALTSLM KKKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.39794
Match:	1f0iA
Description:	Phospholipase D
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.42274246180183	bayes_pls_golite062009
catalytic activity	1.29236214516383	bayes_pls_golite062009
phosphoric diester hydrolase activity	1.25148072945538	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.97354820978871	bayes_pls_golite062009
nucleic acid binding	0.566950403258922	bayes_pls_golite062009
protein binding	0.438178121330569	bayes_pls_golite062009
transferase activity	0.417847571627092	bayes_pls_golite062009
kinase activity	0.41582825017763	bayes_pls_golite062009
DNA binding	0.402372477477629	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.398900256450913	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: