YRC Public Data Repository - Protein Structure Prediction

Protein:	CLR3_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	687 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLR3_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|33115101 - gi\|33115101\|gb\|AAP95013.1\|AF306859_1 putative histone deacetylase [Emericella nidulans]	770.0	[0..10]	[679..82]
gi\|42550807, gi\|... - gi\|46116964\|ref\|XP_384500.1\| hypothetical protein FG04324.1 [Gibberella zeae PH-1], gi\|42550807\|gb\|E...	721.0	[0..12]	[680..12]
gi\|145017965, gi... - gi\|39973555\|ref\|XP_368168.1\| hypothetical protein MGG_01076 [Magnaporthe grisea 70-15], gb\|EAA49418....	701.0	[0..51]	[679..75]
gi\|85082720 - gi\|85082720\|ref\|XP_956974.1\| hypothetical protein [Neurospora crassa OR74A] gi\|28918056, gi\|... - gi\|32414969\|ref\|XP_327964.1\| hypothetical protein [Neurospora crassa], gi\|28918056\|gb\|EAA27738.1\| hy...	700.0	[0..51]	[679..66]
gi\|33115103 - gi\|33115103\|gb\|AAP95014.1\|AF307341_1 putative histone deacetylase [Cochliobolus carbonum]	698.0	[0..1]	[667..58]
gi\|18376165 - gi\|18376165\|emb\|CAD21239.1\| related to histone deacetylase A [Neurospora crassa]	695.0	[0..51]	[679..66]
gi\|49117051, gi\|... - gi\|67902110\|ref\|XP_681311.1\| hypothetical protein AN8042.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	691.0	[0..10]	[679..82]
gi\|151944501 - gi\|151944501\|gb\|EDN62779.1\| histone deacetylase [Saccharomyces cerevisiae YJM789] HDA1_YEAST - Histone deacetylase HDA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HDA1 PE=1 SV=1 HDA1 - Putative catalytic subunit of a class II histone deacetylase complex that also contains Hda2p and Hd...	689.0	[0..48]	[680..49]
gi\|44982418, gi\|... - gi\|45187657\|ref\|NP_983880.1\| ADL216Cp [Ashbya gossypii ATCC 10895], gi\|44982418\|gb\|AAS51704.1\| ADL21... gi\|44982418 - gi\|44982418\|gb\|AAS51704.1\| ADL216Cp [Ashbya gossypii ATCC 10895]	689.0	[0..43]	[680..38]
gi\|83768243 - gi\|83768243\|dbj\|BAE58382.1\| unnamed protein product [Aspergillus oryzae] gi\|169771829 - gi\|169771829\|ref\|XP_001820384.1\| hypothetical protein [Aspergillus oryzae RIB40]	666.0	[0..27]	[678..26]

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Predicted Domain #1

Region A:
Residues: [1-419]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLASNSDGAS TSVKPSDDAV NTVTPWSILL TNNKPMSGSE NTLNNESHEM SQILKKSGLC  60
   61 YDPRMRFHAT LSEVDDHPED PRRVLRVFEA IKKAGYVSNV PSPSDVFLRI PAREATLEEL 120
  121 LQVHSQEMYD RVTNTEKMSH EDLANLEKIS DSLYYNNESA FCARLACGSA IETCTAVVTG 180
  181 QVKNAFAVVR PPGHHAEPHK PGGFCLFNNV SVTARSMLQR FPDKIKRVLI VDWDIHHGNG 240
  241 TQMAFYDDPN VLYVSLHRYE NGRFYPGTNY GCAENCGEGP GLGRTVNIPW SCAGMGDGDY 300
  301 IYAFQRVVMP VAYEFDPDLV IVSCGFDAAA GDHIGQFLLT PAAYAHMTQM LMGLADGKVF 360
  361 ISLEGGYNLD SISTSALAVA QSLLGIPPGR LHTTYACPQA VATINHVTKI QSQYWRCMR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	103.0
Match:	2nvrA
Description:	No description for 2nvrA was found.

Predicted Domain #2

Region A:
Residues: [420-687]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PKHFDANPKD AHVDRLHDVI RTYQAKKLFE DWKITNMPIL RDSVSNVFNN QVLCSSNFFQ  60
   61 KDNLLVIVHE SPRVLGNGTS ETNVLNLNDS LLVDPVSLYV EWAMQQDWGL IDINIPEVVT 120
  121 DGENAPVDIL SEVKELCLYV WDNYVELSIS KNIFFIGGGK AVHGLVNLAS SRNVSDRVKC 180
  181 MVNFLGTEPL VGLKTASEED LPTWYYRHSL VFVSSSNECW KKAKRAKRRY GRLMQSEHTE 240
  241 TSDMMEQHYR AVTQYLLHLL QKARPTSQ

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.12
Match:	2r8bA
Description:	No description for 2r8bA was found.

Predicted functions:

Term	Confidence	Notes
deacetylase activity	6.54075174712552	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	5.11117025144926	bayes_pls_golite062009
hydrolase activity	1.60018186789194	bayes_pls_golite062009
structural molecule activity	1.57651476285011	bayes_pls_golite062009
catalytic activity	1.2983708611085	bayes_pls_golite062009
binding	1.08169264016862	bayes_pls_golite062009
protein binding	0.954507778375691	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.936052349626823	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0.856360387483181	bayes_pls_golite062009
acetyltransferase activity	0.807420416019793	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: