YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|110344245, gi...
Organism:	Escherichia coli 536
Length:	190 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|110344245, gi....

Description	E-value	Query Range	Subject Range
gi\|13362811 - gi\|13362811\|dbj\|BAB36764.1\| transcriptional regulation of gcv operon [Escherichia coli O157:H7 str. ... gi\|13362811 - gi\|13362811\|dbj\|BAB36764.1\| transcriptional regulation of gcv operon [Escherichia coli O157:H7] gi\|209763694, gi... - pir\|\|F65023 gcvR protein - Escherichia coli (strain K-12), pir\|\|A85891 transcription regulation of ... gi\|12516861, gi\|... - gi\|15803002\|ref\|NP_289032.1\| transcriptional regulation of gcv operon [Escherichia coli O157:H7 EDL9... gi\|49176227, gi\|... - gi\|49176227\|ref\|NP_416974.3\| transcriptional regulation of gcv operon [Escherichia coli K12], gb\|AAC... gi\|209913213, gi... - gi\|209919954\|ref\|YP_002294038.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|188488765, gi... - gi\|188493566\|ref\|ZP_03000836.1\| ACT domain protein [Escherichia coli 53638], gi\|188488765\|gb\|EDU6386... gi\|187733494, gi... - gi\|187733494\|ref\|YP_001881271.1\| glycine cleavage system transcriptional repressor [Shigella boydii ... gi\|82777861, gi\|... - gi\|82777861\|ref\|YP_404210.1\| transcriptional regulation of gcv operon [Shigella dysenteriae Sd197], ... gi\|81246338, gi\|... - gi\|82544927\|ref\|YP_408874.1\| GcvR [Shigella boydii Sb227], gi\|81246338\|gb\|ABB67046.1\| GcvR [Shigella... gi\|73856482, gi\|... - gi\|74313005\|ref\|YP_311424.1\| transcriptional regulation of gcv operon [Shigella sonnei Ss046], gi\|73... gi\|157161941, gi... - gi\|157161941\|ref\|YP_001459259.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|157158641, gi... - gi\|157158641\|ref\|YP_001463804.1\| glycine cleavage system transcriptional repressor [Escherichia coli...	170.0	[0..1]	[190..23]
gi\|226901363, gi... - gi\|237704997\|ref\|ZP_04535478.1\| glycine cleavage system transcriptional repressor [Escherichia sp. 3... gi\|91211811, gi\|... - gi\|91211811\|ref\|YP_541797.1\| glycine cleavage system transcriptional repressor [Escherichia coli UTI...	169.0	[0..1]	[190..23]
gi\|26109255, gi\|... - gi\|26248849\|ref\|NP_754889.1\| Glycine cleavage system transcriptional repressor [Escherichia coli CFT...	168.0	[0..1]	[190..23]
gi\|16421032, gi\|... - gi\|16765810\|ref\|NP_461425.1\| gcv operon transcriptional repressor [Salmonella typhimurium LT2], gi\|1...	168.0	[0..1]	[190..23]
gi\|56126885, gi\|... - gi\|56412628\|ref\|YP_149703.1\| glycine cleavage system transcriptional repressor [Salmonella enterica ...	168.0	[0..1]	[190..23]
gi\|16761407 - gi\|16761407\|ref\|NP_457024.1\| glycine cleavage system transcriptional repressor [Salmonella enterica ... gi\|16503707, gi\|... - gi\|25339785\|pir\|\|AF0817 glycine cleavage system transcription repressor STY2728 [imported] - Salmone... gi\|29136521, gi\|... - gi\|29140896\|ref\|NP_804238.1\| glycine cleavage system transcriptional repressor [Salmonella enterica ...	167.0	[0..1]	[190..23]
gi\|62181055, gi\|... - gi\|62181055\|ref\|YP_217472.1\| transcriptional repressor of gcv operon [Salmonella enterica subsp. ent...	167.0	[0..1]	[190..35]
gi\|75196485 - gi\|75196485\|ref\|ZP_00706555.1\| COG2716: Glycine cleavage system regulatory protein [Escherichia coli... gi\|75187226 - gi\|75187226\|ref\|ZP_00700493.1\| COG2716: Glycine cleavage system regulatory protein [Escherichia coli... gi\|75178078 - gi\|75178078\|ref\|ZP_00698137.1\| COG2716: Glycine cleavage system regulatory protein [Shigella boydii ... gi\|83586872 - gi\|83586872\|ref\|ZP_00925503.1\| COG2716: Glycine cleavage system regulatory protein [Escherichia coli... gi\|83570695 - gi\|83570695\|ref\|ZP_00922138.1\| COG2716: Glycine cleavage system regulatory protein [Shigella dysente... gi\|75515818 - gi\|75515818\|ref\|ZP_00737953.1\| COG2716: Glycine cleavage system regulatory protein [Escherichia coli... gi\|75257285 - gi\|75257285\|ref\|ZP_00728809.1\| COG2716: Glycine cleavage system regulatory protein [Escherichia coli... gi\|75240129 - gi\|75240129\|ref\|ZP_00724088.1\| COG2716: Glycine cleavage system regulatory protein [Escherichia coli... gi\|117624675, gi... - gi\|117624675\|ref\|YP_853588.1\| glycine cleavage system transcriptional repressor [Escherichia coli AP... gi\|75237775 - gi\|75237775\|ref\|ZP_00721791.1\| COG2716: Glycine cleavage system regulatory protein [Escherichia coli... gi\|75229196 - gi\|75229196\|ref\|ZP_00715764.1\| COG2716: Glycine cleavage system regulatory protein [Escherichia coli... gi\|75211444 - gi\|75211444\|ref\|ZP_00711534.1\| COG2716: Glycine cleavage system regulatory protein [Escherichia coli...	156.0	[0..11]	[190..2]
gi\|229695028, gi... - gi\|229838662\|ref\|ZP_04458821.1\| DNA-binding transcriptional repressor, regulatory protein accessory ... gi\|229687630, gi... - gi\|229899228\|ref\|ZP_04514371.1\| DNA-binding transcriptional repressor, regulatory protein accessory ... gi\|229701532, gi... - gi\|229895726\|ref\|ZP_04510897.1\| DNA-binding transcriptional repressor, regulatory protein accessory ... gi\|16123240, gi\|... - gi\|218930108\|ref\|YP_002347983.1\| glycine cleavage system transcriptional repressor [Yersinia pestis ... gi\|25339783 - pir\|\|AF0372 glycine cleavage system transcription repressor gcvR [imported] - Yersinia pestis (strai... gi\|161760565 - gi\|161760565\|ref\|YP_071291.2\| glycine cleavage system transcriptional repressor [Yersinia pseudotube... gi\|161511347 - gi\|161511347\|ref\|NP_993998.2\| glycine cleavage system transcriptional repressor [Yersinia pestis bio... gi\|153949947, gi... - gi\|153949947\|ref\|YP_001400226.1\| glycine cleavage system transcriptional repressor [Yersinia pseudot... gi\|149365076, gi... - gi\|149365076\|ref\|ZP_01887111.1\| glycine cleavage system transcriptional repressor [Yersinia pestis C... gi\|167399679, gi... - gi\|167399679\|ref\|ZP_02305203.1\| glycine cleavage system transcriptional repressor [Yersinia pestis b... gi\|165921288, gi... - gi\|165926937\|ref\|ZP_02222769.1\| glycine cleavage system transcriptional repressor [Yersinia pestis b... gi\|229681675, gi... - gi\|229901746\|ref\|ZP_04516868.1\| DNA-binding transcriptional repressor, regulatory protein accessory ... gi\|162100169 - gi\|162100169\|ref\|YP_652164.2\| glycine cleavage system transcriptional repressor [Yersinia pestis Ant...	154.0	[0..1]	[186..1]
gi\|54208728 - gi\|54208728\|gb\|AAV31123.1\| glycine cleavage system transcriptional repressor [Yersinia ruckeri]	154.0	[0..1]	[186..16]

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Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLSSQHYLV ITALGADRPG IVNTITRHVS SCGCNIEDSR LAMLGEEFTF IMLLSGSWNA  60
   61 ITLIESTLPL KGAELDLLIV MKRTTARPRP PMPASVWVQV DVADSPHLIE RFTALFDAHH 120
  121 MNIAELVSRT QPAENERAAQ LHIQITAHSP ASADAANIEQ AFKALCTELN AQGSINVVNY 180
  181 SQHDEQDGVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.30103
Match:	1u8sA
Description:	Crystal structure of putative glycine cleavage system transcriptional repressor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	1.81856869558384	bayes_pls_golite062009
transcription regulator activity	1.38296114573583	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	1.0474189646138	bayes_pls_golite062009
catalytic activity	1.01569611874813	bayes_pls_golite062009
nucleic acid binding	0.562543295273244	bayes_pls_golite062009
binding	0.386656911415569	bayes_pls_golite062009
DNA binding	0.376378714748963	bayes_pls_golite062009
transferase activity	0.07375530569672	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: