YRC Public Data Repository - Protein Structure Prediction

Protein:	RET4_MOUSE
Organism:	Mus musculus
Length:	201 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RET4_MOUSE.

Description	E-value	Query Range	Subject Range
RET4_PIG - Retinol-binding protein 4 OS=Sus scrofa GN=RBP4 PE=1 SV=2	230.0	[0..1]	[201..1]
gi\|73998292 - gi\|73998292\|ref\|XP_534969.2\| PREDICTED: similar to retinol-binding protein 4, plasma precursor [Cani...	229.0	[0..1]	[201..67]
gi\|20141667, gi\|... - sp\|P02753\|RETB_HUMAN Plasma retinol-binding protein precursor (PRBP) (RBP) (PRO2222), gi\|18088326\|gb... gi\|123995765, gi... - gi\|123995765\|gb\|ABM85484.1\| retinol binding protein 4, plasma [synthetic construct], gi\|123980956\|gb...	229.0	[0..1]	[201..1]
gi\|109463849, gi... - gi\|109463849\|ref\|XP_001080229.1\| PREDICTED: similar to Plasma retinol-binding protein precursor (PRB...	227.0	[0..1]	[201..67]
gi\|81674813 - gi\|81674813\|gb\|AAI09816.1\| RBP4 protein [Bos taurus]	222.0	[0..1]	[201..1]
RET4_HORSE - Retinol-binding protein 4 OS=Equus caballus GN=RBP4 PE=2 SV=1	222.0	[0..1]	[201..1]
RET4_RABIT - Retinol-binding protein 4 OS=Oryctolagus cuniculus GN=RBP4 PE=1 SV=2	222.0	[0..1]	[201..1]

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Predicted Domain #1

Region A:
Residues: [1-201]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEWVWALVLL AALGGGSAER DCRVSSFRVK ENFDKARFSG LWYAIAKKDP EGLFLQDNII  60
   61 AEFSVDEKGH MSATAKGRVR LLSNWEVCAD MVGTFTDTED PAKFKMKYWG VASFLQRGND 120
  121 DHWIIDTDYD TFALQYSCRL QNLDGTCADS YSFVFSRDPN GLSPETRRLV RQRQEELCLE 180
  181 RQYRWIEHNG YCQSRPSRNS L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.39794
Match:	1aqbA
Description:	RETINOL-BINDING PROTEIN (RBP) FROM PIG PLASMA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
retinol transporter activity	5.36786048169505	bayes_pls_golite062009
retinoid binding	4.98767549087138	bayes_pls_golite062009
isoprenoid binding	4.86005192942793	bayes_pls_golite062009
binding	2.93830472620404	bayes_pls_golite062009
vitamin transporter activity	2.17605178509363	bayes_pls_golite062009
prostaglandin-D synthase activity	2.01260368661398	bayes_pls_golite062009
odorant binding	1.90612877218228	bayes_pls_golite062009
protein binding	1.23450129884619	bayes_pls_golite062009
retinol binding	0.866894491338918	bayes_pls_golite062009
lipid binding	0.688968384039649	bayes_pls_golite062009
transcription regulator activity	0.492856831386131	bayes_pls_golite062009
fatty acid binding	0.457077174463924	bayes_pls_golite062009
retinoic acid binding	0.00104547816575412	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: