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View Structure Prediction Details

Protein: NECP1_MOUSE
Organism: Mus musculus
Length: 275 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NECP1_MOUSE.

Description E-value Query
Range
Subject
Range
NECAP1 - NECAP endocytosis associated 1
488.0 [0..1] [275..1]
gi|55732012 - gi|55732012|emb|CAH92713.1| hypothetical protein [Pongo abelii]
gi|55732012|emb|... - hypothetical protein [Pongo pygmaeus]
485.0 [0..1] [275..1]
gi|114643284, gi... - gi|114643288|ref|XP_001166796.1| PREDICTED: hypothetical protein isoform 1 [Pan troglodytes], gi|114...
485.0 [0..1] [275..1]
gi|109095493, gi... - gi|109095493|ref|XP_001113313.1| PREDICTED: similar to adaptin-ear-binding coat-associated protein 1...
484.0 [0..1] [275..1]
gi|60359884 - gi|60359884|dbj|BAD90161.1| mFLJ00061 protein [Mus musculus]
481.0 [0..2] [274..1]
NECP1_BOVIN - Adaptin ear-binding coat-associated protein 1 OS=Bos taurus GN=NECAP1 PE=2 SV=1
481.0 [0..1] [275..1]
gi|73997236 - gi|73997236|ref|XP_543832.2| PREDICTED: similar to adaptin-ear-binding coat-associated protein 1 iso...
480.0 [0..1] [275..1]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAELEYESV LCVKPDVSVY RIPPRASNRG YRASDWKLDQ PDWTGRLRIT SKGKIAYIKL  60
   61 EDKVSGELFA QAPVEQYPGI AVETVTDSSR YFVIRIQDGT GRSAFIGIGF TDRGDAFDFN 120
  121 VSLQDHFKWV KQETE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.69897
Match: 1tqzA
Description: Solution structure of NECAP1 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.71359450116612 bayes_pls_golite062009
clathrin binding 2.40957758416782 bayes_pls_golite062009
protein binding 2.32907126599643 bayes_pls_golite062009
transporter activity 1.28986800087234 bayes_pls_golite062009
phospholipid binding 1.09683218092034 bayes_pls_golite062009
substrate-specific transporter activity 0.79883446648737 bayes_pls_golite062009
protein domain specific binding 0.75677415006638 bayes_pls_golite062009
phosphoinositide binding 0.71817045430443 bayes_pls_golite062009
cytoskeletal protein binding 0.268141992393579 bayes_pls_golite062009
lipid binding 0.179561240451969 bayes_pls_golite062009
pyrophosphatase activity 0.0611639610381174 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0524559849408587 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0498422520006935 bayes_pls_golite062009
actin binding 0.0485598963526399 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [136-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISKESQEMDN RPKLDLGFKE GQTIKLSIGN ITAKKGGASK PRASGTGGLS LLPPPPGGKV  60
   61 TIPPPSSSVA ISNHVTPPPI PKSNHGGNDS DILLDLDSPA PVSTSAPAPV STSNDLWGDF 120
  121 STASSSVPNQ APQPSNWVQF 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle