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View Structure Prediction Details

Protein: MSGN1_MOUSE
Organism: Mus musculus
Length: 188 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSGN1_MOUSE.

Description E-value Query
Range
Subject
Range
gi|149050925, gi... - gi|157817991|ref|NP_001103021.1| mesogenin 1 [Rattus norvegicus], gi|149050925|gb|EDM03098.1| rCG623...
126.0 [0..1] [188..1]
gi|109102112 - gi|109102112|ref|XP_001105593.1| PREDICTED: similar to mesogenin 1 [Macaca mulatta]
111.0 [0..1] [186..1]
gi|55594803 - gi|55594803|ref|XP_525696.1| PREDICTED: similar to mesogenin 1 [Pan troglodytes]
110.0 [0..1] [186..1]
MSGN1 - mesogenin 1
gi|225000072 - gi|225000072|gb|AAI72301.1| Mesogenin 1 [synthetic construct]
109.0 [0..1] [186..1]
gi|76661229 - gi|76661229|ref|XP_599820.2| PREDICTED: similar to pMesogenin1 [Bos taurus]
109.0 [0..1] [187..1]
gi|16611800 - gi|16611800|gb|AAL27367.1| myogenic factor 5 [Equus caballus]
105.0 [0..45] [182..10]
gi|33604049, gi|... - gi|5726232|gb|AAD48371.1|AF119220_1 microphthalmia-related protein [Danio rerio], gi|33604049|gb|AAH...
104.0 [0..1] [186..86]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNLGETFLS LEDGLDSSDT AGLLASWDWK SRARPLELVQ ESPTQSLSPA PSLESYSEVA  60
   61 LPCGHSGAST GGSDGYGSHE AAGLVELDYS MLAFQPPYLH TAG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [104-188]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLKGQKGSKV KMSVQRRRKA SEREKLRMRT LADALHTLRN YLPPVYSQRG QPLTKIQTLK  60
   61 YTIKYIGELT DLLNSSGREP RPQSV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1mdyA
Description: Myod B/HLH domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.04189889011459 bayes_pls_golite062009
DNA binding 1.34047429825414 bayes_pls_golite062009
transcription regulator activity 1.24166705689751 bayes_pls_golite062009
transcription factor activity 1.21289741269658 bayes_pls_golite062009
nucleic acid binding 1.12120276328559 bayes_pls_golite062009
protein binding 0.90375176425983 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle