YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|13360244, gi\|...
Organism:	Escherichia coli O157:H7 str. Sakai
Length:	382 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|13360244, gi|....

Description	E-value	Query Range	Subject Range
GAL1_SALDC - Galactokinase OS=Salmonella dublin (strain CT_02021853) GN=galK PE=3 SV=1 gi\|200391087, gi... - gi\|200391087\|ref\|ZP_03217698.1\| galactokinase [Salmonella enterica subsp. enterica serovar Virchow s... gi\|204930110, gi... - gi\|204930110\|ref\|ZP_03221131.1\| galactokinase [Salmonella enterica subsp. enterica serovar Javiana s... gi\|29142528, gi\|... - gi\|29142528\|ref\|NP_805870.1\| galactokinase [Salmonella enterica subsp. enterica serovar Typhi str. T... gi\|16759699 - gi\|16759699\|ref\|NP_455316.1\| galactokinase [Salmonella enterica subsp. enterica serovar Typhi str. C... GAL1_SALTI - Galactokinase OS=Salmonella typhi GN=galK PE=3 SV=1 GAL1_SALTI - Galactokinase OS=Salmonella typhi GN=galK PE=3 SV=1 gi\|238913334 - gi\|238913334\|ref\|ZP_04657171.1\| galactokinase [Salmonella enterica subsp. enterica serovar Tennessee... gi\|214001892 - gi\|214001892\|ref\|ZP_03412627.1\| galactokinase [Salmonella enterica subsp. enterica serovar Typhi str... GAL1_SALEP - Galactokinase OS=Salmonella enteritidis PT4 (strain P125109) GN=galK PE=3 SV=1 gi\|213023145 - gi\|213023145\|ref\|ZP_03337592.1\| galactokinase [Salmonella enterica subsp. enterica serovar Typhi str... gi\|213427697 - gi\|213427697\|ref\|ZP_03360447.1\| galactokinase [Salmonella enterica subsp. enterica serovar Typhi str... gi\|213613330 - gi\|213613330\|ref\|ZP_03371156.1\| galactokinase [Salmonella enterica subsp. enterica serovar Typhi str...	362.0	[0..1]	[382..1]
gi\|205327714, gi... - gi\|205327714\|gb\|EDZ14478.1\| galactokinase [Salmonella enterica subsp. enterica serovar 4,[5],12:i:- ... GAL1_SALTY - Galactokinase OS=Salmonella typhimurium GN=galK PE=3 SV=2 GAL1_SALNS - Galactokinase OS=Salmonella newport (strain SL254) GN=galK PE=3 SV=1 lcl\|NC_016856.1_... - [gene=galK] [protein=galactokinase] [protein_id=YP_005236493.1] [location=complement(838713..839861)... GAL1_SALTY - Galactokinase OS=Salmonella typhimurium GN=galK PE=3 SV=2 GAL1_SALTY - Galactokinase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=galK PE=3 SV=2	361.0	[0..1]	[382..1]
gi\|59803287 - gi\|59803287\|gb\|AAX07752.1\| galactokinase [Klebsiella pneumoniae] gi\|238893786, gi... - gi\|238893786\|ref\|YP_002918520.1\| galactokinase [Klebsiella pneumoniae NTUH-K2044], gi\|238546102\|dbj\|...	360.0	[0..1]	[382..1]
gi\|86516618 - gi\|86516618\|gb\|ABC98001.1\| GalK [Shigella boydii]	359.0	[0..1]	[382..1]
gi\|86516662 - gi\|86516662\|gb\|ABC98023.1\| GalK [Shigella dysenteriae]	359.0	[0..1]	[382..1]
GAL1_ECOUT - Galactokinase OS=Escherichia coli (strain UTI89 / UPEC) GN=galK PE=3 SV=1 gi\|227884282, gi... - gi\|227884282\|ref\|ZP_04002087.1\| galactokinase [Escherichia coli 83972], gi\|227839034\|gb\|EEJ49500.1\| ... gi\|226898497, gi... - gi\|237707287\|ref\|ZP_04537768.1\| galactokinase [Escherichia sp. 3_2_53FAA], gi\|226898497\|gb\|EEH84756.... GAL1_ECO45 - Galactokinase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=galK PE=3 SV=1 GAL1_ECOL6 - Galactokinase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=galK PE=3 SV=3 gi\|75237093, gi\|... - gi\|75237093\|ref\|ZP_00721147.1\| COG0153: Galactokinase [Escherichia coli F11], gi\|191174194\|ref\|ZP_03... GAL1_ECOK1 - Galactokinase OS=Escherichia coli O1:K1 / APEC GN=galK PE=3 SV=1 GAL1_ECOL6 - Galactokinase OS=Escherichia coli O6 GN=galK PE=3 SV=3 GAL1_ECOL5 - Galactokinase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=galK PE=3 SV=1	359.0	[0..1]	[382..1]
GAL1_SALCH - Galactokinase OS=Salmonella choleraesuis GN=galK PE=3 SV=1 GAL1_SALCH - Galactokinase OS=Salmonella choleraesuis GN=galK PE=3 SV=1 GAL1_SALCH - Galactokinase OS=Salmonella choleraesuis (strain SC-B67) GN=galK PE=3 SV=1	359.0	[0..1]	[382..1]
gi\|86516676, gi\|... - gi\|86516678\|gb\|ABC98031.1\| GalK [Shigella flexneri], gi\|86516676\|gb\|ABC98030.1\| GalK [Shigella flexn...	358.0	[0..1]	[382..1]

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Predicted Domain #1

Region A:
Residues: [1-382]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKEKTQSL FANAFGYPAT HTIQAPGRVN LIGEHTDYND GFVLPCAIDY QTVISCAPRD  60
   61 DRKVRVMAAD YENQLDEFSL DAPIVAHENY QWANYVRGVV KHLQLRNNSF GGVDMVISGN 120
  121 VPQGAGLSSS ASLEVAVGTV LQQLYHLPLD GAQIALNGQE AENQFVGCNC GIMDQLISAL 180
  181 GKKDHALLID CRSLGTKAVS MPKGVAVVII NSNFKRTLVG SEYNTRREQC ETGARFFQQP 240
  241 ALRDVTIEEF NAVAHELDPI VAKRVRHILT ENARTVEAAS ALEQGDLKRM GELMAESHAS 300
  301 MRDDFEITVP QIDTLVEIVK AVIGDKGGVR MTGGGFGGCI VALIPEELVP AVQQAVAEQY 360
  361 EAKTGIKETF YVCKPSQGAG QC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	77.522879
Match:	1wuuA
Description:	crystal structure of human galactokinase complexed with MgAMPPNP and galactose
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
galactokinase activity	2.78881744973459	bayes_pls_golite062009
catalytic activity	0.878454819018611	bayes_pls_golite062009
hydrolase activity	0.740929677099368	bayes_pls_golite062009
nuclease activity	0.658641254758609	bayes_pls_golite062009
ribonuclease activity	0.545200648734771	bayes_pls_golite062009
binding	0.189327444560056	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: