YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|13362811
Organism:	Escherichia coli O157:H7 str. Sakai
Length:	212 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|13362811.

Description	E-value	Query Range	Subject Range
gi\|226901363, gi... - gi\|237704997\|ref\|ZP_04535478.1\| glycine cleavage system transcriptional repressor [Escherichia sp. 3... gi\|91211811, gi\|... - gi\|91211811\|ref\|YP_541797.1\| glycine cleavage system transcriptional repressor [Escherichia coli UTI...	145.0	[0..1]	[212..1]
gi\|26109255, gi\|... - gi\|26248849\|ref\|NP_754889.1\| Glycine cleavage system transcriptional repressor [Escherichia coli CFT...	145.0	[0..1]	[212..1]
gi\|110594248, gi... - gi\|110594248\|ref\|ZP_01382595.1\| formyltetrahydrofolate deformylase [Acidovorax sp. JS42], gi\|1103364...	144.0	[0..17]	[209..110]
gi\|16421032, gi\|... - gi\|16765810\|ref\|NP_461425.1\| gcv operon transcriptional repressor [Salmonella typhimurium LT2], gi\|1...	142.0	[0..1]	[212..1]
gi\|16761407 - gi\|16761407\|ref\|NP_457024.1\| glycine cleavage system transcriptional repressor [Salmonella enterica ... gi\|16503707, gi\|... - gi\|25339785\|pir\|\|AF0817 glycine cleavage system transcription repressor STY2728 [imported] - Salmone... gi\|29136521, gi\|... - gi\|29140896\|ref\|NP_804238.1\| glycine cleavage system transcriptional repressor [Salmonella enterica ...	142.0	[0..1]	[212..1]
gi\|83723946, gi\|... - gi\|83749369\|ref\|ZP_00946364.1\| Formyltetrahydrofolate deformylase [Ralstonia solanacearum UW551], gi...	141.0	[0..5]	[209..10]
gi\|56126885, gi\|... - gi\|56412628\|ref\|YP_149703.1\| glycine cleavage system transcriptional repressor [Salmonella enterica ...	141.0	[0..1]	[212..1]
gi\|48786510, gi\|... - gi\|91781734\|ref\|YP_556940.1\| formyltetrahydrofolate deformylase [Burkholderia xenovorans LB400], gi\|...	141.0	[0..25]	[209..1]
gi\|169772989 - gi\|169772989\|ref\|XP_001820963.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83768824 - gi\|83768824\|dbj\|BAE58961.1\| unnamed protein product [Aspergillus oryzae]	140.0	[0..30]	[209..3]
gi\|84362886 - gi\|84362886\|ref\|ZP_00987497.1\| COG0788: Formyltetrahydrofolate hydrolase [Burkholderia dolosa AUO158...	138.0	[0..25]	[209..1]

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Predicted Domain #1

Region A:
Residues: [1-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLYACFFYAF LKNNSPLKGI TSLTLSSQHY LVITALGADR PGIVNTITRH VSSCGCNIED  60
   61 SRLAMLGEEF TFIMLLSGSW NAITLIESTL PLKGAELDLL IVMKRTTARP RPPMPASVWV 120
  121 QVDVADSPHL IERFTALFDA HHMNIAELVS RTQPAENERA AQLHIQITAH SPASADAANI 180
  181 EQAFKALCTE LNAQGSINVV NYSQHDEQDG VK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.221849
Match:	1u8sA
Description:	Crystal structure of putative glycine cleavage system transcriptional repressor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	1.81856869558384	bayes_pls_golite062009
transcription regulator activity	1.38296114573583	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	1.0474189646138	bayes_pls_golite062009
catalytic activity	1.01569611874813	bayes_pls_golite062009
nucleic acid binding	0.562543295273244	bayes_pls_golite062009
binding	0.386656911415569	bayes_pls_golite062009
DNA binding	0.376378714748963	bayes_pls_golite062009
transferase activity	0.07375530569672	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: