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View Structure Prediction Details

Protein: CCL3_MOUSE
Organism: Mus musculus
Length: 92 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CCL3_MOUSE.

Description E-value Query
Range
Subject
Range
CCL3_RAT - C-C motif chemokine 3 OS=Rattus norvegicus GN=Ccl3 PE=1 SV=1
120.0 [0..1] [92..1]
gi|533241 - gi|533241|gb|AAA40146.1| T cell secreted protein
118.0 [0..1] [92..1]
gi|55977442 - gi|55977442|gb|AAV68490.1| CCL3/MIP1alpha [Mesocricetus auratus]
117.0 [0..1] [92..1]
gi|164665382, gi... - gi|57527998|ref|NP_001009579.1| chemokine (C-C motif) ligand 3-like 1 [Sus scrofa], gi|49354682|gb|A...
115.0 [0..1] [92..1]
CCL4_MACMU - C-C motif chemokine 4 OS=Macaca mulatta GN=CCL4 PE=2 SV=1
115.0 [0..1] [91..1]
CCL13 - chemokine (C-C motif) ligand 13
gi|60654807, gi|... - gi|60654809|gb|AAX31969.1| chemokine (C-C motif) ligand 13 [synthetic construct], gi|60654807|gb|AAX...
115.0 [0..1] [92..1]
CCL4_BOVIN - C-C motif chemokine 4 OS=Bos taurus GN=CCL4 PE=3 SV=1
114.0 [0..1] [91..1]
gi|114668172 - gi|114668172|ref|XP_001174525.1| PREDICTED: small inducible cytokine A13 [Pan troglodytes]
114.0 [0..1] [92..1]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVSTTALAV LLCTMTLCNQ VFSAPYGADT PTACCFSYSR KIPRQFIVDY FETSSLCSQP  60
   61 GVIFLTKRNR QICADSKETW VQEYITDLEL NA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.69897
Match: 1hrjA
Description: RANTES (regulated upon activation, normal T-cell expressed and secreted)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytokine activity 8.07273475133641 bayes_pls_golite062009
chemokine receptor binding 7.19574940007631 bayes_pls_golite062009
chemokine activity 7.19574940007631 bayes_pls_golite062009
G-protein-coupled receptor binding 7.12866319987718 bayes_pls_golite062009
receptor binding 5.70505228637425 bayes_pls_golite062009
protein binding 3.96178206863622 bayes_pls_golite062009
interleukin-8 receptor binding 3.86135397575984 bayes_pls_golite062009
binding 3.44333267537536 bayes_pls_golite062009
chemoattractant activity 3.05299139114464 bayes_pls_golite062009
heparin binding 2.48790323783525 bayes_pls_golite062009
glycosaminoglycan binding 1.80091312295242 bayes_pls_golite062009
CCR2 chemokine receptor binding 1.78317158345185 bayes_pls_golite062009
polysaccharide binding 1.28416986663426 bayes_pls_golite062009
pattern binding 1.02739535268516 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.0107537553708 bayes_pls_golite062009
CCR chemokine receptor binding 0.697359799598971 bayes_pls_golite062009
carbohydrate binding 0.14673741350408 bayes_pls_golite062009
transporter activity 0.0541029584618528 bayes_pls_golite062009

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