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View Structure Prediction Details

Protein: EMD_MOUSE
Organism: Mus musculus
Length: 259 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EMD_MOUSE.

Description E-value Query
Range
Subject
Range
gi|74204219 - gi|74204219|dbj|BAE39870.1| unnamed protein product [Mus musculus]
320.0 [0..1] [259..1]
EMD_RAT - Emerin OS=Rattus norvegicus GN=Emd PE=1 SV=1
307.0 [0..1] [259..1]
gi|74356375 - gi|74356375|gb|AAI04568.1| EMD protein [Bos taurus]
298.0 [0..1] [259..1]
gi|109132796 - gi|109132796|ref|XP_001090376.1| PREDICTED: emerin (Emery-Dreifuss muscular dystrophy) [Macaca mulat...
293.0 [0..1] [259..1]
gi|61372645, gi|... - gi|61372651|gb|AAX43883.1| emerin [synthetic construct], gi|61372645|gb|AAX43882.1| emerin [syntheti...
282.0 [0..1] [255..1]
EMD - emerin
gi|60655441, gi|... - gi|60655441|gb|AAX32284.1| emerin [synthetic construct], gi|60655439|gb|AAX32283.1| emerin [syntheti...
281.0 [0..1] [255..1]

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Predicted Domain #1
Region A:
Residues: [1-64]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDYAVLSDT ELAAVLRQYN IPHGPIVGST RKLYEKKIFE YETQRRRLLP PNSSSSSFSY  60
   61 QFSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1jeiA
Description: Inner nuclear membrane protein emerin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
lamin binding 4.39382764264433 bayes_pls_golite062009
binding 2.48575835933363 bayes_pls_golite062009
protein binding 1.25020901551294 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [65-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDSAAVDSDM YDLPKKEDAL LYQSKDYNDD YYEESYLTTK TYGEPESVGM SKSFRQPGTS  60
   61 LVDADTFHHQ VRDDIFSSLE EEGKD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [150-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RERLIYGQDS AYQSIAHYRP ISNVSRSSLG LSYYPTSSTS SVSSSSSSPS SWLTRRAIRP  60
   61 EKQAPAAALG QDRQVPLWGQ LLLFLVFAAF LLFVYYSIQA EEGNPFWMDP 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle