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View Structure Prediction Details

Protein: FBpp0293023
Organism: Drosophila melanogaster
Length: 1918 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0293023.

Description E-value Query
Range		 Subject
Range
gi|115939157, gi... - gi|115939157|ref|XP_001196401.1| PREDICTED: similar to ankyrin 2,3/unc44, partial [Strongylocentrotu...
 1138.0 [0..10] [1099..33]

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Predicted Domain #1
Region A:
Residues: [1-116] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASCAPVIVW NGAQFTASSR ELEQLRRDYG LDARMLEATL VPRYKRHKPQ AAARNDHVRV  60
   61 TKEQQSDWIL KQDRSTNVSQ VNFHPWAGAH FDLVPWRRTR SALDLTAVED YNHGLV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [117-291] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPKSLKGLEK LELRQQRRRL QRARSTHQGL RRLVRVRLIF SIELRHKRME VLRKSSLPVR  60
   61 VFEQRFALSE NESAAYERIL LDANAGVDQH VGYFSKRQVV TSNRESNEEL VVDFASETEA 120
  121 DEKADEQPEK EEAQYATIAP AEKGGSAAVP DKESGQVPCV KCRDIAIKLR TINDY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [292-687] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALNSNLHLSH NTKLNNLHSN KLLHSNQSHS SSINPSTRMH SHQLDSYLGG VGSMMNLGGM  60
   61 GQVGQMYHPG SVSGSERPNG GALALHYAAA RGCLDCVQLL VAASVDICYF STINVKKGLL 120
  121 GRMTTSLTSY RRSKQKSKSN NDIHTIIATE VVTAAILSSS VHSSSTGSEI GDGGQGNTSL 180
  181 IEEAAAQDQS SEEQDRQHQH AKDPLAQTEM NHHPHSHHQR KSAVEVVRQQ MDDDGDQDSN 240
  241 DDDETMPMMS GVGRKEQNNR RSVVSANTQM DNDVTPVYLA AQEGHLEVLK FLVLEAGGSL 300
  301 YVRARDGMAP IHAASQMGCL DCLKWMVQDQ GVDPNLRDGD GATPLHFAAS RGHLSVVRWL 360
  361 LNHGAKLSLD KYGKSPINDA AENQQVECLN VLVQHG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 101.0
Match: 1n11A
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.30812396303844 bayes_pls_golite062009
actin binding 3.15358758538214 bayes_pls_golite062009
structural constituent of cytoskeleton 2.4948065111495 bayes_pls_golite062009
binding 2.03195138036959 bayes_pls_golite062009
actin filament binding 1.8758804992293 bayes_pls_golite062009
protein binding 1.6716587413544 bayes_pls_golite062009
myosin binding 1.55894148251645 bayes_pls_golite062009
myosin phosphatase activity 0.991228379874891 bayes_pls_golite062009
structural constituent of muscle 0.304639267984357 bayes_pls_golite062009
structural molecule activity 0.242743465134414 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [688-864] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSVDYNGKSS SQRHKSQQQL HQQHQQQQQQ QQQQHLSSSC NSNSNSSKQT SRSNTIKSKS  60
   61 SSTLSSDVEP FYLHPPALAG GSGGSGMGLG MGMGMGMGMS MGLGISRKNS DALYSQQSRS 120
  121 SSEKLYNGSS SLGGNPGGNS SSGGGGVGGG GGSGGALLPN DGLYVNPMRN GGMYNTP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.0
Match: 1awcB
Description: GA bindinig protein (GABP) beta 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.30812396303844 bayes_pls_golite062009
actin binding 3.15358758538214 bayes_pls_golite062009
structural constituent of cytoskeleton 2.4948065111495 bayes_pls_golite062009
binding 2.03195138036959 bayes_pls_golite062009
actin filament binding 1.8758804992293 bayes_pls_golite062009
protein binding 1.6716587413544 bayes_pls_golite062009
myosin binding 1.55894148251645 bayes_pls_golite062009
myosin phosphatase activity 0.991228379874891 bayes_pls_golite062009
structural constituent of muscle 0.304639267984357 bayes_pls_golite062009
structural molecule activity 0.242743465134414 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [865-1063] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPNGSISGES FFLHDPQDII YNRVRDLFVD SDCSSSVKQH GKSHAHQLLQ SKAGNAMTIQ  60
   61 ADVHSSSSGA GSGSDESVSI SSSFNSPKQQ QQLRSQSFNR HGSSSNISAS GNIKNNNYKA 120
  121 HKGKPSNQNG GGDHDYEDIY LVREESRKQH QQQQQHQLQQ QQQLQHQATQ QQQQQQQQQQ 180
  181 QLQHKYNVGR SRSRDSGSH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1064-1304] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRSASASSTR STDIVLQYSN HHLNNKRNMN NNSNMNNSSS NIAQSSSSNN NNNSLLNRNK  60
   61 SHSIIGLHSS KYESSLKDNY SAKNVNLKNQ LLNGGIKSDT YESVCPPEDV AERTKQTHKN 120
  121 SMIRNNLADA SSNNNTSGSI NNISNIGNMN GGNQSSRNLK RVSSAPPMQN LAVVNGPPPP 180
  181 PLPPPLRAPV QQQRNNLSVD QPNSMTGNNG IYKKNVFGPN QGPTNANGTG GAAPPPVPAP 240
  241 N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1305-1362] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVATEAVDSD SGLEVVEEPS LRPSELVRGN HNRTMSTISA NKKAKLLNAG STNGSSIA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1363-1554] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASSDDSQSRY GGSVHAANGS AANGHFYGYS EGNKNQGSNG NGNGNGNGGG GNYHSHPNQP  60
   61 HYATGQPHQY TPSLYGGGSS AEDHYELTQQ QQQIYGETHL PSGQRTGGPN LVNKQLVLPF 120
  121 VPPSFPNKSQ DGVTHLIKPS EYLKSISIDK RSCPSSARST DTEDYMQIQI AQQQSHPHQH 180
  181 QHHPHPHPHP HH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1555-1688] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHQLHGMGEQ PPLPPPPPPL PHGMLPPQPP MGPPMGVAGG QDATMSGKSH KPKKPHGSAP  60
   61 NSQDTATRKQ HQPLSAISIQ DLNSVQLRRT DTQKVPKPYQ MPARSLSMQC LTSSTETYLK 120
  121 SDLIAELKIS KDIP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1689-1795] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIKKMKVEQQ MASRMDSEHY MEITKQFSGN NYVDQIPERD QAGNAIPDWK RQMMAKKAAE  60
   61 RAKKDFEERM AQEAESRRLS QIPQWKRDLL ARREETENKL KAAIYTP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1796-1918] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVEENNRVAD TWRLKNRAMS IDNININLAG MEQHYQQIQF QQKQQQLQLG NKENHVDPKG  60
   61 ADQDQEHGVG IGSGVGNANS GVIGGQELID PSEGSQGRAE EEEDNIIPWR AQLRKTNSRL 120
  121 SLI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle