YRC Public Data Repository - Protein Structure Prediction

Protein:	AREG_MOUSE
Organism:	Mus musculus
Length:	248 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AREG_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|47523808, gi\|... - gi\|47523808\|ref\|NP_999541.1\| amphiregulin [Sus scrofa], gi\|13540808\|gb\|AAK27728.1\| amphiregulin long...	167.0	[0..1]	[248..1]
gi\|109074490 - gi\|109074490\|ref\|XP_001101978.1\| PREDICTED: similar to Amphiregulin precursor (AR) (Colorectum cell-...	166.0	[0..1]	[248..1]
gi\|82917251, gi\|... - gi\|94383392\|ref\|XP_901497.2\| PREDICTED: fat tumor suppressor homolog isoform 7 [Mus musculus], gi\|82...	166.0	[0..13]	[244..4019]
gi\|114594252 - gi\|114594252\|ref\|XP_517224.2\| PREDICTED: similar to Amphiregulin precursor (AR) (Colorectum cell-der...	165.0	[0..1]	[248..1]
gi\|60817324, gi\|... - gi\|61358541\|gb\|AAX41584.1\| amphiregulin [synthetic construct], gi\|60817324\|gb\|AAX36418.1\| amphiregul...	164.0	[0..1]	[248..1]
gi\|13929168, gi\|... - gi\|4426629\|gb\|AAD20459.1\| protocadherin [Rattus norvegicus], gi\|13929168\|ref\|NP_114007.1\| FAT tumor ...	164.0	[0..13]	[244..4018]
AREGB, AREG - amphiregulin, amphiregulin B gi\|123987712, gi... - gi\|61357021\|gb\|AAX41321.1\| amphiregulin [synthetic construct], gi\|123999106\|gb\|ABM87136.1\| amphiregu...	161.0	[0..1]	[248..1]
gi\|73979548 - gi\|73979548\|ref\|XP_532835.2\| PREDICTED: similar to FAT tumor suppressor 1 precursor [Canis familiari...	159.0	[0..13]	[244..4020]

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Predicted Domain #1

Region A:
Residues: [1-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTPLLPLAR SVLLLLVLGS GHYAAALELN DPSSGKGESL SGDHSAGGLE LSVGREVSTI  60
   61 SEMPSGSELS TGDYDYSEEY DNEPQISGYI IDDSVRVEQV IKPKKNKTEG EKSTEKPKRK 120
  121 KKGGKNGKGR RNKKKKNPCT AKFQNFCIHG ECRYIENLEV VTCNCHQDYF GERCGEKSMK 180
  181 THSEDDKDLS KIAVVAVTIF VSAIILAAIG IGIVITVHLW KRYFREYEGE TEERRRLRQE 240
  241 NGTVHAIA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.154902
Match:	1jv2B
Description:	Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits