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View Structure Prediction Details

Protein: TUBGCP2
Organism: Homo sapiens
Length: 902 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TUBGCP2.

Description E-value Query
Range
Subject
Range
GCP2_PONAB - Gamma-tubulin complex component 2 OS=Pongo abelii GN=TUBGCP2 PE=2 SV=1
GCP2_PONPY - Gamma-tubulin complex component 2 - Pongo pygmaeus (Orangutan)
997.0 [0..1] [902..1]
gi|62898904 - gi|62898904|dbj|BAD97306.1| tubulin, gamma complex associated protein 2 variant [Homo sapiens]
993.0 [0..1] [902..1]
gi|74145105 - gi|74145105|dbj|BAE27420.1| unnamed protein product [Mus musculus]
988.0 [0..1] [902..1]
gi|157820617, gi... - gi|62641573|ref|XP_219470.3| PREDICTED: similar to tubulin, gamma complex associated protein 2 [Ratt...
979.0 [0..1] [902..1]
gi|32766545, gi|... - gi|41056243|ref|NP_956416.1| tubulin, gamma complex associated protein 2 [Danio rerio], gi|32766545|...
904.0 [0..1] [881..1]
gi|109091041, gi... - gi|109091043|ref|XP_001093066.1| PREDICTED: tubulin, gamma complex associated protein 2 isoform 2 [M...
900.0 [0..1] [902..1]
gi|53130558, gi|... - gi|57529863|ref|NP_001006496.1| tubulin, gamma complex associated protein 2 [Gallus gallus], gi|5313...
872.0 [0..1] [879..1]

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Predicted Domain #1
Region A:
Residues: [1-58]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEFRIHHDV NELLSLLRVH GGDGAEVYID LLQKNRTPYV TTTVSAHSAK VKIAEFSR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.577 N/A N/A a.4.1 Homeodomain-like
View Download 0.559 N/A N/A d.230.3 Amyloid beta a4 protein copper binding domain (domain 2)
View Download 0.516 N/A N/A d.11.1 Penicillin-binding protein 2x (pbp-2x), c-terminal domain
View Download 0.504 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.444 N/A N/A g.59.1 Zinc-binding domain of translation initiation factor 2 beta
View Download 0.436 N/A N/A a.4.1 Homeodomain-like
View Download 0.427 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.426 N/A N/A a.4.1 Homeodomain-like
View Download 0.413 N/A N/A d.11.1 Penicillin-binding protein 2x (pbp-2x), c-terminal domain
View Download 0.411 N/A N/A d.58.3 Protease propeptides/inhibitors

Predicted Domain #2
Region A:
Residues: [59-205]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPEDFLKKYD ELKSKNTRNL DPLVYLLSKL TEDKETLQYL QQNAKERAEL AAAAVGSSTT  60
   61 SINVPAAASK ISMQELEELR KQLGSVATGS TLQQSLELKR KMLRDKQNKK NSGQHLPIFP 120
  121 AWVYERPALI GDFLIGAGIS TDTALPI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.381 c.66.1 S-adenosyl-L-methionine-dependent methyltransferases
View Download 0.374 c.66.1 S-adenosyl-L-methionine-dependent methyltransferases
View Download 0.365 a.74.1 Cyclin-like
View Download 0.318 a.74.1 Cyclin-like
View Download 0.276 d.110.4 SNARE-like
View Download 0.274 d.110.4 SNARE-like
View Download 0.274 a.74.1 Cyclin-like
View Download 0.241 a.26.1 4-helical cytokines

Predicted Domain #3
Region A:
Residues: [206-415]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTLPLASQES AVVEDLLYVL VGVDGRYVSA QPLAGRQSRT FLVDPNLDLS IRELVHRILP  60
   61 VAASYSAVTR FIEEKSSFEY GQVNHALAAA MRTLVKEHLI LVSQLEQLHR QGLLSLQKLW 120
  121 FYIQPAMRTM DILASLATSV DKGECLGGST LSLLHDRSFS YTGDSQAQEL CLYLTKAASA 180
  181 PYFEVLEKWI YRGIIHDPYS EFMVEEHELR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [416-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KERIQEDYND KYWDQRYTIV QQQIPSFLQK MADKILSTGK YLNVVRECGH DVT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.377 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.371 a.4.7 Ribosomal protein L11, C-terminal domain
View Download 0.317 a.5.2 UBA-like
View Download 0.279 a.5.2 UBA-like
View Download 0.271 a.5.2 UBA-like
View Download 0.248 a.5.2 UBA-like
View Download 0.241 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.221 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain

Predicted Domain #5
Region A:
Residues: [469-572]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CPVAKEIIYT LKERAYVEQI EKAFNYASKV LLDFLMEEKE LVAHLRSIKR YFLMDQGDFF  60
   61 VHFMDLAEEE LRKPVEDITP PRLEALLELA LRMSTANTDP FKDD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.889 a.186.1 Description not found.
View Download 0.838 a.29.14 Description not found.
View Download 0.823 a.29.8 Description not found.
View Download 0.795 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.791 a.3.1 Cytochrome c
View Download 0.702 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.682 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.675 a.156.1 S13-like H2TH domain
View Download 0.673 a.29.2 Bromodomain
View Download 0.543 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.437 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.376 a.163.1 Crustacean CHH/MIH/GIH neurohormone

Predicted Domain #6
Region A:
Residues: [573-702]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKIDLMPHDL ITQLLRVLAI ETKQEKAMAH ADPTELALSG LEAFSFDYIV KWPLSLIINR  60
   61 KALTRYQMLF RHMFYCKHVE RQLCSVWISN KTAKQHSLHS AQWFAGAFTL RQRMLNFVQN 120
  121 IQYYMMFEVM 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.974 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.855 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.854 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.837 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.830 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.812 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.794 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.715 N/A N/A f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.700 N/A N/A a.47.2 t-snare proteins
View Download 0.688 N/A N/A a.24.9 alpha-catenin/vinculin

Predicted Domain #7
Region A:
Residues: [703-902]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPTWHILEKN LKSASNIDDV LGHHTGFLDT CLKDCMLTNP ELLKVFSKLM SVCVMFTNCM  60
   61 QKFTQSMKLD GELGGQTLEH STVLGLPAGA EERARKELAR KHLAEHADTV QLVSGFEATI 120
  121 NKFDKNFSAH LLDLLARLSI YSTSDCEHGM ASVISRLDFN GFYTERLERL SAERSQKATP 180
  181 QVPVLRGPPA PAPRVAVTAQ 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle