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View Structure Prediction Details

Protein: PELI2
Organism: Homo sapiens
Length: 420 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PELI2.

Description E-value Query
Range		 Subject
Range
gi|114653181 - gi|114653181|ref|XP_522860.2| PREDICTED: pellino 2 [Pan troglodytes]
 0.0 [1..420] [1..420]
gi|76660216 - gi|76660216|ref|XP_612354.2| PREDICTED: similar to pellino 2 [Bos taurus]
 0.0 [1..420] [1..420]
gi|149033568, gi... - gi|157822359|ref|NP_001100729.1| pellino 2 [Rattus norvegicus], gi|149033568|gb|EDL88366.1| similar ...
 0.0 [1..420] [1..419]
PELI2_MOUSE - E3 ubiquitin-protein ligase pellino homolog 2 OS=Mus musculus GN=Peli2 PE=1 SV=2
 0.0 [1..420] [1..419]
gi|49119164, gi|... - gi|49119164|gb|AAH72891.1| MGC80329 protein [Xenopus laevis], gi|148234615|ref|NP_001085528.1| MGC80...
 0.0 [1..420] [1..419]
gi|38649366, gi|... - gi|45361111|ref|NP_989171.1| pellino homolog 1 [Xenopus (Silurana) tropicalis], gi|38649366|gb|AAH63...
 0.0 [1..420] [1..419]
CCDS1876.1_1 - null
tr|G3H131|G3H131... - Protein pellino-like 1 OS=Cricetulus griseus GN=I79_003854 PE=4 SV=1
PELI1 - pellino homolog 1 (Drosophila)
tr|M3XET5|M3XET5... - Pellino E3 ubiquitin protein ligase 1 OS=Felis catus GN=PELI1 PE=4 SV=1
 0.0 [1..420] [1..418]
gi|57093365 - gi|57093365|ref|XP_538508.1| PREDICTED: similar to pellino protein [Canis familiaris]
 0.0 [1..420] [1..418]

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Predicted Domain #1
Region A:
Residues: [1-196] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSPGQEEHC APNKEPVKYG ELVVLGYNGA LPNGDRGRRK SRFALYKRPK ANGVKPSTVH  60
   61 VISTPQASKA ISCKGQHSIS YTLSRNQTVV VEYTHDKDTD MFQVGRSTES PIDFVVTDTI 120
  121 SGSQNTDEAQ ITQSTISRFA CRIVCDRNEP YTARIFAAGF DSSKNIFLGE KAAKWKNPDG 180
  181 HMDGLTTNGV LVMHPR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [197-330] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGFTEESQPG VWREISVCGD VYTLRETRSA QQRGKLVESE TNVLQDGSLI DLCGATLLWR  60
   61 TADGLFHTPT QKHIEALRQE INAARPQCPV GLNTLAFPSI NRKEVVEEKQ PWAYLSCGHV 120
  121 HGYHNWGHRS DTEA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.957
Match: 1jm7A
Description: brca1 RING domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.06923986676721 bayes_pls_golite062009
protein binding 1.48593945455888 bayes_pls_golite062009
small conjugating protein ligase activity 0.324292450240439 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.248014157054608 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [331-420] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NERECPMCRT VGPYVPLWLG CEAGFYVDAG PPTHAFTPCG HVCSEKSAKY WSQIPLPHGT  60
   61 HAFHAACPFC ATQLVGEQNC IKLIFQGPID

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.17
Match: 2ecnA
Description: No description for 2ecnA was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle