| Protein: | TNF |
| Organism: | Homo sapiens |
| Length: | 233 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TNF.
| Description | E-value | Query Range |
Subject Range |
|
|
1.0E-98 | [1..233] | [1..233] |
|
|
3.0E-98 | [1..233] | [1..233] |
|
|
3.0E-98 | [1..233] | [1..233] |
|
|
2.0E-97 | [1..233] | [1..233] |
|
|
5.0E-97 | [1..233] | [1..233] |
|
|
6.0E-97 | [1..233] | [1..232] |
|
|
1.0E-96 | [1..233] | [1..233] |
|
|
7.0E-96 | [1..233] | [1..233] |
|
|
9.0E-96 | [1..233] | [1..233] |
|
Region A: Residues: [1-233] |
1 11 21 31 41 51
| | | | | |
1 MSTESMIRDV ELAEEALPKK TGGPQGSRRC LFLSLFSFLI VAGATTLFCL LHFGVIGPQR 60
61 EEFPRDLSLI SPLAQAVRSS SRTPSDKPVA HVVANPQAEG QLQWLNRRAN ALLANGVELR 120
121 DNQLVVPSEG LYLIYSQVLF KGQGCPSTHV LLTHTISRIA VSYQTKVNLL SAIKSPCQRE 180
181 TPEGAEAKPW YEPIYLGGVF QLEKGDRLSA EINRPDYLDF AESGQVYFGI IAL
|
| Detection Method: |  |
| Confidence: | 64.045757 |
| Match: | 1a8mA |
| Description: | Tumor necrosis factor (TNF) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| tumor necrosis factor receptor binding | 4.41551127334596 | bayes_pls_golite062009 |
| receptor binding | 3.37824597039547 | bayes_pls_golite062009 |
| tumor necrosis factor receptor superfamily binding | 3.27382150819697 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 2.99764886866547 | bayes_pls_golite062009 |
| protein binding | 2.25413201891408 | bayes_pls_golite062009 |
| cytokine activity | 2.15273244126886 | bayes_pls_golite062009 |
| binding | 1.76110862494815 | bayes_pls_golite062009 |
| CD40 receptor binding | 1.32291890442774 | bayes_pls_golite062009 |
| peptidase inhibitor activity | 1.28185157337226 | bayes_pls_golite062009 |
| endopeptidase inhibitor activity | 1.2326564264318 | bayes_pls_golite062009 |
| cell surface binding | 1.12145675554147 | bayes_pls_golite062009 |
| structural molecule activity | 0.402748748247022 | bayes_pls_golite062009 |
| eukaryotic cell surface binding | 0.3981620493951 | bayes_pls_golite062009 |
| hormone activity | 0.0434508002092211 | bayes_pls_golite062009 |
| caspase inhibitor activity | 0.0237319623798404 | bayes_pls_golite062009 |
