YRC Public Data Repository - Protein Structure Prediction

Protein:	OIP5
Organism:	Homo sapiens
Length:	229 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OIP5.

Description	E-value	Query Range	Subject Range
gi\|2815610 - gi\|2815610\|gb\|AAC39561.1\| Opa-interacting protein OIP5 [Homo sapiens]	0.0	[1..229]	[3..231]
gi\|114656440 - gi\|114656440\|ref\|XP_510321.2\| PREDICTED: Opa interacting protein 5 isoform 2 [Pan troglodytes]	0.0	[1..229]	[1..229]
gi\|109080728 - gi\|109080728\|ref\|XP_001100229.1\| PREDICTED: Opa interacting protein 5 [Macaca mulatta]	0.0	[1..229]	[1..229]
gi\|74000175 - gi\|74000175\|ref\|XP_850812.1\| PREDICTED: similar to Opa-interacting protein 5 [Canis familiaris]	0.0	[1..229]	[1..229]
gi\|76627525 - gi\|76627525\|ref\|XP_588370.2\| PREDICTED: similar to Opa-interacting protein 5 (Cancer/testis antigen ...	0.0	[1..229]	[1..229]
MS18B_MOUSE - Protein Mis18-beta OS=Mus musculus GN=Oip5 PE=2 SV=1	0.0	[32..229]	[26..223]
gi\|109470664 - gi\|109470664\|ref\|XP_001080849.1\| PREDICTED: similar to Opa-interacting protein 5 [Rattus norvegicus]	1.0E-98	[33..229]	[25..221]

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Predicted Domain #1

Region A:
Residues: [1-229]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAQPLRHRS RCATPPRGDF CGGTERAIDQ ASFTTSMEWD TQVVKGSSPL GPAGLGAEEP  60
   61 AAGPQLPSWL QPERCAVFQC AQCHAVLADS VHLAWDLSRS LGAVVFSRVT NNVVLEAPFL 120
  121 VGIEGSLKGS TYNLLFCGSC GIPVGFHLYS THAALAALRG HFCLSSDKMV CYLLKTKAIV 180
  181 NASEMDIQNV PLSEKIAELK EKIVLTHNRL KSLMKILSEV TPDQSKPEN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.992
Match:	1l1dA
Description:	C-terminal MsrB domain of peptide methionine sulfoxide reductase PilB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.01583557026263	bayes_pls_golite062009
protein binding	0.403925330913665	bayes_pls_golite062009
catalytic activity	0.00921124779125454	bayes_pls_golite062009
transcription regulator activity	0.00310095000769373	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: