YRC Public Data Repository - Protein Structure Prediction

Protein:	TXNDC17
Organism:	Homo sapiens
Length:	123 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TXNDC17.

Description	E-value	Query Range	Subject Range
gi\|83776783 - gi\|83776783\|gb\|ABC46707.1\| chloroplast thioredoxin M-type [Arachis hypogaea]	4.0E-26	[3..122]	[73..178]
gi\|76812139, gi\|... - gi\|76812139\|ref\|YP_333769.1\| thioredoxin 1 [Burkholderia pseudomallei 1710b], gi\|76581592\|gb\|ABA5106...	4.0E-26	[2..121]	[38..143]
TRXM_PEA - Thioredoxin M-type, chloroplastic OS=Pisum sativum PE=2 SV=1	4.0E-26	[3..122]	[65..170]
TRXM4_ARATH - Thioredoxin M4, chloroplastic OS=Arabidopsis thaliana GN=At3g15360 PE=2 SV=2	1.0E-25	[2..121]	[83..188]
gi\|83721362, gi\|... - gi\|83721362\|ref\|YP_442739.1\| thioredoxin [Burkholderia thailandensis E264], gi\|83655187\|gb\|ABC39250....	1.0E-25	[2..121]	[38..143]
gi\|160872103, gi... - gi\|94494048\|ref\|ZP_01301251.1\| hypothetical protein Rgryl_01000578 [Rickettsiella grylli], gi\|160872...	1.0E-25	[7..122]	[6..108]
gi\|95928472, gi\|... - gi\|95928472\|ref\|ZP_01311219.1\| thioredoxin [Desulfuromonas acetoxidans DSM 684], gi\|95135262\|gb\|EAT1...	1.0E-25	[3..122]	[2..107]
gi\|116057647 - gi\|116057647\|emb\|CAL53850.1\| Thioredoxin (ISS) [Ostreococcus tauri]	1.0E-25	[8..122]	[114..214]

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Predicted Domain #1

Region A:
Residues: [1-123]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARYEEVSVS GFEEFHRAVE QHNGKTIFAY FTGSKDAGGK SWCPDCVQAE PVVREGLKHI  60
   61 SEGCVFIYCQ VGEKPYWKDP NNDFRKNLKV TAVPTLLKYG TPQKLVESEC LQANLVEMLF 120
  121 SED

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.09691
Match:	1wouA
Description:	Crystal Structure of human Trp14
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.672192331361968	bayes_pls_golite062009
binding	0.618139748326926	bayes_pls_golite062009
protein-disulfide reductase activity	0.570446901634881	bayes_pls_golite062009
protein binding	0.134341907247724	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: