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View Structure Prediction Details

Protein: DPPA5
Organism: Homo sapiens
Length: 116 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DPPA5.

Description E-value Query
Range
Subject
Range
gi|94408060 - gi|94408060|ref|XP_996242.1| PREDICTED: similar to developmental pluripotency associated 5 [Mus musc...
4.0E-46 [1..116] [479..594]
gi|73973739 - gi|73973739|ref|XP_538999.2| PREDICTED: hypothetical protein XP_538999 [Canis familiaris]
1.0E-42 [1..116] [201..316]
gi|34854832, gi|... - gi|34854832|ref|XP_229957.2| PREDICTED: similar to developmental pluripotency associated 5 [Rattus n...
4.0E-42 [1..116] [1..116]
gi|109071700 - gi|109071700|ref|XP_001112340.1| PREDICTED: similar to developmental pluripotency associated 5 [Maca...
6.0E-40 [1..116] [1..116]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTLPARRHI PPWVKVPEDL KDPEVFQVQT RLLKAIFGPD GSRIPYIEQV SKAMLELKAL  60
   61 ESSDLTEVVV YGSYLYKLRT KWMLQSMAEW HRQRQERGML KLAEAMNALE LGPWMK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.221849
Match: 1wvnA
Description: Crsytal Structure of domain 3 of human alpha polyC binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.51118372606632 bayes_pls_golite062009
binding 3.39099792965392 bayes_pls_golite062009
RNA binding 2.44646347925345 bayes_pls_golite062009
protein binding 1.06558436580734 bayes_pls_golite062009
transcription regulator activity 1.03950315057479 bayes_pls_golite062009
mRNA binding 0.95227803909413 bayes_pls_golite062009
DNA binding 0.856382540865261 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle