| Protein: | TDP1 |
| Organism: | Homo sapiens |
| Length: | 608 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TDP1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..608] | [1..608] |
|
|
0.0 | [1..608] | [1..609] |
|
|
0.0 | [1..608] | [1..609] |
|
|
0.0 | [1..608] | [1..603] |
|
|
0.0 | [35..608] | [104..677] |
|
|
0.0 | [1..608] | [1..609] |
|
Region A: Residues: [1-150] |
1 11 21 31 41 51
| | | | | |
1 MSQEGDYGRW TISSSDESEE EKPKPDKPST SSLLCARQGA ANEPRYTCSE AQKAAHKRKI 60
61 SPVKFSNTDS VLPPKRQKSG SQEDLGWCLS SSDDELQPEM PQKQAEKVVI KKEKDISAPN 120
121 DGTAQRTENH GAPACHRLKE EEDEYETSGE
|
| Detection Method: |  |
| Confidence: | 1.6 |
| Match: | 2j63A |
| Description: | No description for 2j63A was found. |
|
Region A: Residues: [151-608] |
1 11 21 31 41 51
| | | | | |
1 GQDIWDMLDK GNPFQFYLTR VSGVKPKYNS GALHIKDILS PLFGTLVSSA QFNYCFDVDW 60
61 LVKQYPPEFR KKPILLVHGD KREAKAHLHA QAKPYENISL CQAKLDIAFG THHTKMMLLL 120
121 YEEGLRVVIH TSNLIHADWH QKTQGIWLSP LYPRIADGTH KSGESPTHFK ADLISYLMAY 180
181 NAPSLKEWID VIHKHDLSET NVYLIGSTPG RFQGSQKDNW GHFRLKKLLK DHASSMPNAE 240
241 SWPVVGQFSS VGSLGADESK WLCSEFKESM LTLGKESKTP GKSSVPLYLI YPSVENVRTS 300
301 LEGYPAGGSL PYSIQTAEKQ NWLHSYFHKW SAETSGRSNA MPHIKTYMRP SPDFSKIAWF 360
361 LVTSANLSKA AWGALEKNGT QLMIRSYELG VLFLPSAFGL DSFKVKQKFF AGSQEPMATF 420
421 PVPYDLPPEL YGSKDRPWIW NIPYVKAPDT HGNMWVPS
|
| Detection Method: | |
| Confidence: | 1000.0 |
| Match: | 1mu7A |
| Description: | Tyrosyl-DNA phosphodiesterase TDP1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| 3'-tyrosyl-DNA phosphodiesterase activity | 1.46693175347055 | bayes_pls_golite062009 |
| tyrosyl-DNA phosphodiesterase activity | 1.46693175347055 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.41591686174898 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.29668490323599 | bayes_pls_golite062009 |
| single-stranded DNA binding | 1.29429720882252 | bayes_pls_golite062009 |
| catalytic activity | 1.29236214516383 | bayes_pls_golite062009 |
| binding | 1.26667168593698 | bayes_pls_golite062009 |
| nucleic acid binding | 0.926017334343152 | bayes_pls_golite062009 |
| DNA binding | 0.840595330626189 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.235198647671849 | bayes_pls_golite062009 |
| protein binding | 0.162885453822356 | bayes_pls_golite062009 |
| kinase activity | 0.10314500262782 | bayes_pls_golite062009 |
